Sectors
Construction, buildings and roads 10
Agent or job IARC label Established links Suspected links Evaluated
Asbestos Known cause Group 1 4 Larynx (voice-box) cancer, Lung cancer, Mesothelioma (lining of lungs/abdomen), Ovarian cancer4 Colon cancer, Rectal cancer, Stomach cancer, Throat (pharynx) cancerVol. 100C, 2009
Coal-tar pitch Known cause Group 1 1 Lung cancer1 Bladder cancerVol. 100F, 2009
Painting (occupational) Known cause Group 1 3 Bladder cancer, Lung cancer, Mesothelioma (lining of lungs/abdomen)0 Vol. 100F, 2009
Pentachlorophenol (wood preservative) Known cause Group 1 2 Multiple myeloma (a blood cancer), Non-Hodgkin lymphoma (all types)0 Vol. 117, 2016
Silica dust (quartz or cristobalite) Known cause Group 1 1 Lung cancer0 Vol. 100C, 2009
Wood dust Known cause Group 1 2 Nasal & sinus cancer, Nasopharyngeal cancer (upper throat)0 Vol. 100C, 2009
Bitumens (oxidized, roofing) Probable cause Group 2A 0 6 Larynx (voice-box) cancer, Lung cancer, Mouth cancer, Oesophageal (food-pipe) cancer, Throat (pharynx) cancer, Upper aerodigestive tract (mouth/throat/voice-box)Vol. 103, 2011
Creosotes Probable cause Group 2A 0 2 Lung cancer, Skin cancer (non-melanoma)Vol. 92, 2005
Bitumens (hard, mastic asphalt work) Possible cause Group 2B 0 6 Larynx (voice-box) cancer, Lung cancer, Mouth cancer, Oesophageal (food-pipe) cancer, Throat (pharynx) cancer, Upper aerodigestive tract (mouth/throat/voice-box)Vol. 103, 2011
Carpentry and joinery Possible cause Group 2B 0 1 Nasal & sinus cancerSuppl. 7, 1987
Coal, coke, oil and gas 7
Agent or job IARC label Established links Suspected links Evaluated
Coal gasification Known cause Group 1 1 Lung cancer0 Vol. 100F, 2009
Coal-tar distillation Known cause Group 1 1 Skin cancer (non-melanoma)0 Vol. 100F, 2009
Coke production Known cause Group 1 1 Lung cancer0 Vol. 100F, 2009
Mineral oils (untreated or mildly treated) Known cause Group 1 1 Skin cancer (non-melanoma)0 Vol. 100F, 2009
Shale oils Known cause Group 1 1 Skin cancer (non-melanoma)0 Vol. 100F, 2009
Soot (chimney sweeping) Known cause Group 1 2 Lung cancer, Skin cancer (non-melanoma)1 Bladder cancerVol. 100F, 2009
Petroleum refining (occupational) Probable cause Group 2A 0 3 Leukaemia (all types), Skin cancer (melanoma), Skin cancer (non-melanoma)Vol. 45, 1988
Chemicals, plastics and rubber 25
Agent or job IARC label Established links Suspected links Evaluated
1,3-Butadiene Known cause Group 1 3 Leukaemia (all types), Lymphoma (all types), Multiple myeloma (a blood cancer)0 Vol. 100F, 2009
2-Naphthylamine Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
4-Aminobiphenyl Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
Acrylonitrile Known cause Group 1 1 Lung cancer1 Bladder cancerVol. 136, 2024
Auramine production Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
Benzidine Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
Bis(chloromethyl)ether (BCME) Known cause Group 1 1 Lung cancer0 Vol. 100F, 2009
Isopropyl alcohol manufacture (strong acids) Known cause Group 1 1 Nasal & sinus cancer0 Vol. 100F, 2009
Magenta production Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
ortho-Toluidine Known cause Group 1 1 Bladder cancer0 Vol. 100F, 2009
Rubber-manufacturing work Known cause Group 1 5 Bladder cancer, Leukaemia (all types), Lung cancer, Lymphoma (all types), Stomach cancer3 Larynx (voice-box) cancer, Oesophageal (food-pipe) cancer, Prostate cancerVol. 100F, 2009
Strong acid mists Known cause Group 1 1 Larynx (voice-box) cancer1 Lung cancerVol. 100F, 2009
Sulfur mustard (mustard gas) Known cause Group 1 1 Lung cancer1 Larynx (voice-box) cancerVol. 100F, 2009
Trichloroethylene (TCE) Known cause Group 1 1 Kidney cancer3 Bile-duct cancer, Liver cancer, Non-Hodgkin lymphoma (all types)Vol. 106, 2012
Vinyl chloride Known cause Group 1 1 Liver cancer0 Vol. 100F, 2009
1,1,1-Trichloroethane Probable cause Group 2A 0 1 Multiple myeloma (a blood cancer)Vol. 130, 2021
2-Mercaptobenzothiazole Probable cause Group 2A 0 1 Bladder cancerVol. 115, 2016
4-Chloro-ortho-toluidine Probable cause Group 2A 0 1 Bladder cancerVol. 99, 2008
Chlorinated toluenes and benzoyl chloride Probable cause Group 2A 0 1 Lung cancerVol. 71, 1998
Dichloromethane (paint stripper) Probable cause Group 2A 0 2 Bile-duct cancer, Non-Hodgkin lymphoma (all types)Vol. 110, 2014
Dimethylformamide (DMF) Probable cause Group 2A 0 1 Testicular cancerVol. 115, 2016
Hydrazine Probable cause Group 2A 0 1 Lung cancerVol. 115, 2016
Styrene Probable cause Group 2A 0 3 Leukaemia (all types), Lymphoma (all types), Multiple myeloma (a blood cancer)Vol. 121, 2018
Polychlorophenols & their sodium salts (mixed exposures) Possible cause Group 2B 0 2 Non-Hodgkin lymphoma (all types), Soft-tissue sarcomaVol. 71, 1998
Silicon carbide fibres Possible cause Group 2B 0 1 Lung cancerVol. 111, 2014
Cleaning, health care and laboratories 4
Agent or job IARC label Established links Suspected links Evaluated
Ethylene oxide Known cause Group 1 0 4 Breast cancer, Chronic lymphocytic leukaemia, Multiple myeloma (a blood cancer), Non-Hodgkin lymphoma (all types)Vol. 100F, 2009
Formaldehyde Known cause Group 1 4 Acute myeloid leukaemia (a blood cancer), Chronic myeloid leukaemia, Nasopharyngeal cancer (upper throat), Other acute non-lymphocytic leukaemia1 Nasal & sinus cancerVol. 100F, 2009
Tetrachloroethylene (PERC) Probable cause Group 2A 0 1 Bladder cancerVol. 106, 2012
Dry-cleaning work Possible cause Group 2B 0 2 Bladder cancer, Oesophageal (food-pipe) cancerVol. 63, 1995
Printing, textiles, leather and glass 5
Hair and beauty 1
Agent or job IARC label Established links Suspected links Evaluated
Hairdressing / barbering Probable cause Group 2A 0 1 Bladder cancerVol. 99, 2008
Emergency services 1
Agent or job IARC label Established links Suspected links Evaluated
Firefighter (occupational) Known cause Group 1 2 Bladder cancer, Mesothelioma (lining of lungs/abdomen)5 Colon cancer, Non-Hodgkin lymphoma (all types), Prostate cancer, Skin cancer (melanoma), Testicular cancerVol. 132, 2022
Shift work 1
Agent or job IARC label Established links Suspected links Evaluated
Night-shift work Probable cause Group 2A 0 4 Breast cancer, Colon cancer, Prostate cancer, Rectal cancerVol. 124, 2019
Farming and pest control 1
Parents’ work and children 1
Agent or job IARC label Established links Suspected links Evaluated
Mother working as a painter Known cause Group 1 0 1 Childhood leukaemia (all types)Vol. 100F, 2009
Not on this page? The cancer tool’s search covers all 185 agents on the map, and the 874 others IARC evaluated without naming a cancer site.
Beyond cancer
Eight workplace risks for other chronic diseases .
Work is also linked to heart, lung, kidney and joint disease. The Chronic Disease Evidence Explorer grades how sure the evidence is that each risk factor causes a disease, and eight of its risk factors come from work. Its grades are its own and differ from IARC’s labels.