GBD 2021 Risk Factors15 links
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet (London, England) · 2024
Lancet Commission on dementia 202415 links
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
Lancet (London, England) · 2024
Burden of Proof: smoking8 links
Health effects associated with smoking: a Burden of Proof study
Nature medicine · 2022
Blood Pressure Lowering Treatment Trialists8 links
Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
Lancet (London, England) · 2021
INTERSTROKE7 links
Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study
Lancet (London, England) · 2016
Umbrella review of diet and type 2 diabetes incidence6 links
Role of diet in type 2 diabetes incidence: umbrella review of meta-analyses of prospective observational studies.
BMJ (Clinical research ed.) · 2019
BMI and 14 cardiovascular conditions, UK Biobank MR6 links
Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study.
European heart journal · 2020
Umbrella review: food insecurity and health5 links
The Association Between Food Insecurity and Adverse Health Outcomes in Adults: An Umbrella Review of Systematic Reviews and Meta-Analyses.
Nutrition reviews · 2026
MR meta-analysis: lifestyle and back pain5 links
Associations between lifestyle-related risk factors and back pain: a systematic review and meta-analysis of Mendelian randomization studies.
BMC musculoskeletal disorders · 2024
Mendelian randomisation of lifestyle and metabolic factors for NAFLD5 links
Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study.
European journal of epidemiology · 2022
Smoking and 14 cardiovascular diseases: Mendelian randomisation5 links
Genetic predisposition to smoking in relation to 14 cardiovascular diseases.
European heart journal · 2020
Intensive vs standard glucose lowering: meta-analysis of 11 trials (2024)5 links
Glycaemic control and macrovascular and microvascular outcomes: A systematic review and meta-analysis of trials investigating intensive glucose-lowering strategies in people with type 2 diabetes.
Diabetes, obesity & metabolism · 2024
BMI and waist-to-hip ratio with CHD, stroke subtypes and diabetes: MR5 links
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.
Circulation · 2017
Burden of Proof: secondhand smoke4 links
Health effects associated with exposure to secondhand smoke: a Burden of Proof study
Nature medicine · 2024
Cholesterol Treatment Trialists' Collaboration4 links
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
Lancet (London, England) · 2010
INTERHEART4 links
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Lancet (London, England) · 2004
PREDIMED (republished)4 links
Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts
The New England journal of medicine · 2018
WHO global air quality guidelines4 links
WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide
World Health Organization · 2021
Umbrella review: ultra-processed food4 links
Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses.
BMJ (Clinical research ed.) · 2024
Pooled cohorts: cardiovascular risk factors and VTE4 links
Association of Traditional Cardiovascular Risk Factors With Venous Thromboembolism: An Individual Participant Data Meta-Analysis of Prospective Studies.
Circulation · 2016
Mendelian randomisation: modifiable risk factors and aortic valve stenosis, UK Biobank4 links
Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants.
Nutrients · 2022
Sleep duration and cardiovascular outcomes meta-analysis4 links
Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies.
European heart journal · 2011
Sleep duration dose-response meta-analysis4 links
Relationship of Sleep Duration With All-Cause Mortality and Cardiovascular Events: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
Journal of the American Heart Association · 2017
Fruit and vegetable dose-response meta-analysis4 links
Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality-a systematic review and dose-response meta-analysis of prospective studies.
International journal of epidemiology · 2017
Sleep disturbances vs traditional diabetes risk factors4 links
Sleep disturbances compared to traditional risk factors for diabetes development: Systematic review and meta-analysis.
Sleep medicine reviews · 2015
Modifiable pathways in Alzheimer's disease: Mendelian randomisation4 links
Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis.
BMJ (Clinical research ed.) · 2017
Prospective Studies Collaboration: blood pressure3 links
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
Lancet (London, England) · 2002
Emerging Risk Factors Collaboration: diabetes3 links
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
Lancet (London, England) · 2010
VITAL trial3 links
Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
The New England journal of medicine · 2019
China Kadoorie Biobank alcohol MR3 links
Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China
Lancet (London, England) · 2019
SAVE trial (CPAP)3 links
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
The New England journal of medicine · 2016
D-Health trial3 links
The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality
The lancet. Diabetes & endocrinology · 2022
Salt Substitute and Stroke Study3 links
Effect of Salt Substitution on Cardiovascular Events and Death
The New England journal of medicine · 2021
Short sleep and health outcomes meta-analysis3 links
Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression.
Sleep medicine · 2016
Sweetened drinks and incident type 2 diabetes3 links
Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction.
BMJ (Clinical research ed.) · 2015
Eczema and smoking3 links
Association of atopic dermatitis with smoking: A systematic review and meta-analysis.
Journal of the American Academy of Dermatology · 2016
Meta-analysis: DASH-style diet and cardiovascular disease incidence3 links
Effects of Dietary Approaches to Stop Hypertension (DASH)-style diet on fatal or nonfatal cardiovascular diseases--incidence: a systematic review and meta-analysis on observational prospective studies.
Nutrition (Burbank, Los Angeles County, Calif.) · 2013
Education and income and cardiovascular outcomes meta-analysis3 links
Effects of education and income on cardiovascular outcomes: A systematic review and meta-analysis.
European journal of preventive cardiology · 2017
Blood pressure lowering meta-analysis (per 10 mmHg)3 links
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.
Lancet (London, England) · 2016
Red and processed meat and CHD meta-analysis3 links
Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis.
Circulation · 2010
Food groups and CHD/stroke dose-response meta-analysis3 links
Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies.
Critical reviews in food science and nutrition · 2017
ERFC: major lipids and apolipoproteins3 links
Major lipids, apolipoproteins, and risk of vascular disease.
JAMA · 2009
ERFC: BMI and abdominal adiposity3 links
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies.
Lancet (London, England) · 2011
Nuts and legumes and incident IHD meta-analysis3 links
Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis.
The American journal of clinical nutrition · 2014
CHANCES: smoking and cardiovascular events in older adults3 links
Impact of smoking and smoking cessation on cardiovascular events and mortality among older adults: meta-analysis of individual participant data from prospective cohort studies of the CHANCES consortium.
BMJ (Clinical research ed.) · 2015
Air pollution and adult asthma incidence meta-analysis3 links
Ambient air pollution exposure and adult asthma incidence: a systematic review and meta-analysis.
The Lancet. Planetary health · 2024
Umbrella review: diet and neurodegenerative disorders3 links
Dietary Factors and Neurodegenerative Disorders: An Umbrella Review of Meta-Analyses of Prospective Studies.
Adv Nutr · 2020
Pooled analysis of metabolic risk factors by age (PSC and APCSC)3 links
The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis.
PloS one · 2013
Cardiometabolic factors and chronic kidney disease: trans-ethnic MR3 links
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
International journal of epidemiology · 2022
Atlas of risk factors for type 2 diabetes: wide-angled Mendelian randomisation3 links
An atlas on risk factors for type 2 diabetes: a wide-angled Mendelian randomisation study.
Diabetologia · 2020
Burden of Proof: red meat2 links
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study
Nature medicine · 2022
Burden of Proof: vegetables2 links
Health effects associated with vegetable consumption: a Burden of Proof study
Nature medicine · 2022
Women's Health Initiative2 links
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial
JAMA · 2002
Diabetes Prevention Program2 links
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
The New England journal of medicine · 2002
GBD chronic kidney disease2 links
Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Lancet (London, England) · 2020
Umbrella review: environmental risks for MS2 links
Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses.
The Lancet. Neurology · 2015
Smoking and venous thromboembolism2 links
Current and former smoking and risk for venous thromboembolism: a systematic review and meta-analysis.
PLoS medicine · 2013
Adiposity and gallbladder disease2 links
Body mass index, abdominal fatness and the risk of gallbladder disease.
European journal of epidemiology · 2015
Long working hours and heart disease and stroke2 links
Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals.
Lancet (London, England) · 2015
E-cigarettes and respiratory and cardiovascular risk2 links
How effective are electronic cigarettes for reducing respiratory and cardiovascular risk in smokers? A systematic review.
Harm reduction journal · 2020
Factors associated with sarcopenia2 links
Associated Factors of Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
Nutrients · 2021
Eggs and cardiovascular risk, dose-response2 links
Egg consumption and cardiovascular risk: a dose-response meta-analysis of prospective cohort studies.
European journal of nutrition · 2020
Tobacco in pregnancy and eczema in the child2 links
Maternal tobacco exposure during pregnancy and atopic dermatitis in offspring: A systematic review and meta-analysis.
Journal of the European Academy of Dermatology and Venereology · 2024
Phthalates in pregnancy and allergic disease in children2 links
Association of prenatal exposure to phthalates with risks of asthma, wheeze, and allergic diseases during childhood: a systematic review and meta-analysis.
Journal of environmental health science & engineering · 2025
Umbrella review: plastic-associated chemicals2 links
An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.
Annals of global health · 2024
Smoking and periodontitis2 links
Effect of Smoking on Periodontitis: A Systematic Review and Meta-regression.
American journal of preventive medicine · 2018
Quitting smoking and periodontitis2 links
Impact of Smoking Cessation on Periodontitis: A Systematic Review and Meta-analysis of Prospective Longitudinal Observational and Interventional Studies.
Nicotine & tobacco research · 2019
Oral health and diabetes systematic review2 links
Oral health and diabetes: a systematic review and meta-analysis
The Lancet. Public health · 2026
Smoking and erectile dysfunction2 links
Smoking and risk of erectile dysfunction: systematic review of observational studies with meta-analysis.
PloS one · 2013
Plant-based dietary patterns and cardiovascular disease2 links
Association between Plant-Based Dietary Patterns and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.
Nutrients · 2021
Whole grain dose-response meta-analysis2 links
Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies.
BMJ (Clinical research ed.) · 2016
Meta-analysis: psoriasis and smoking2 links
Psoriasis and smoking: a systematic review and meta-analysis.
The British journal of dermatology · 2014
Meta-analysis: body-mass index, physical activity and diverticular disease2 links
Body mass index and physical activity and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies.
European journal of nutrition · 2017
Umbrella review: non-sugar-sweetened beverages and chronic disease2 links
Non-Sugar-Sweetened Beverages and Risk of Chronic Diseases: An Umbrella Review of Meta-analyses of Prospective Cohort Studies.
Nutrition reviews · 2025
Meta-analysis: television viewing, type 2 diabetes and cardiovascular disease2 links
Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis.
JAMA · 2011
Toxic metals and cardiovascular disease meta-analysis2 links
Environmental toxic metal contaminants and risk of cardiovascular disease: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2018
Pre-eclampsia and later cardiovascular disease meta-analysis2 links
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2007
Preeclampsia and future cardiovascular health meta-analysis2 links
Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.
Circulation. Cardiovascular quality and outcomes · 2017
Heat exposure and cardiovascular outcomes meta-analysis2 links
Heat exposure and cardiovascular health outcomes: a systematic review and meta-analysis.
The Lancet. Planetary health · 2022
Ambient temperature and cardiovascular hospitalisation meta-analysis2 links
Ambient temperature and risk of cardiovascular hospitalization: An updated systematic review and meta-analysis.
The Science of the total environment · 2016
Periodontitis, tooth number and CHD meta-analysis2 links
Periodontitis and Number of Teeth in the Risk of Coronary Heart Disease: An Updated Meta-Analysis.
Medical science monitor : international medical journal of experimental and clinical research · 2021
Sex differences in SES and CVD meta-analysis2 links
Sex differences in the relationship between socioeconomic status and cardiovascular disease: a systematic review and meta-analysis.
Journal of epidemiology and community health · 2017
CTT: statins in people at low risk2 links
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials.
Lancet (London, England) · 2012
OSA and vascular outcomes meta-analysis2 links
Association of obstructive sleep apnoea with the risk of vascular outcomes and all-cause mortality: a meta-analysis.
BMJ open · 2017
OSA and cardiovascular risk meta-analysis2 links
Obstructive sleep apnea and cardiovascular risk: meta-analysis of prospective cohort studies.
Atherosclerosis · 2013
OSA and CVD dose-response meta-analysis2 links
Obstructive sleep apnea and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies.
International journal of cardiology · 2013
Prospective Studies Collaboration: BMI2 links
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies.
Lancet (London, England) · 2009
Second-hand smoke and IHD/stroke meta-analysis2 links
Meta-analysis of the association between second-hand smoke exposure and ischaemic heart diseases, COPD and stroke.
BMC public health · 2015
24-hour urinary sodium and cardiovascular risk pooled cohorts2 links
24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk.
The New England journal of medicine · 2021
Sodium intake and cardiovascular outcomes dose-response meta-analysis2 links
Association of sodium intake and major cardiovascular outcomes: a dose-response meta-analysis of prospective cohort studies.
BMC cardiovascular disorders · 2018
Physical activity and cardiovascular disease meta-analysis2 links
Physical activity and risk of cardiovascular disease--a meta-analysis of prospective cohort studies.
International journal of environmental research and public health · 2012
Carbohydrate quality and health series2 links
Carbohydrate quality and human health: a series of systematic reviews and meta-analyses.
Lancet (London, England) · 2019
Mediterranean diet and CVD meta-analysis2 links
A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal?
Critical reviews in food science and nutrition · 2017
Mediterranean diet, CVD and mortality meta-analysis2 links
Mediterranean diet, cardiovascular disease and mortality in diabetes: A systematic review and meta-analysis of prospective cohort studies and randomized clinical trials.
Critical reviews in food science and nutrition · 2019
CKD Prognosis Consortium: eGFR, albuminuria and outcomes2 links
Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis.
JAMA · 2023
Alcohol and incident atrial fibrillation2 links
Alcohol and incident atrial fibrillation - A systematic review and meta-analysis.
International journal of cardiology · 2017
Alcohol and atrial fibrillation dose-response meta-analysis (JACC)2 links
Alcohol consumption and risk of atrial fibrillation: a prospective study and dose-response meta-analysis.
Journal of the American College of Cardiology · 2014
Umbrella review of non-genetic AF risk factors2 links
Environmental factors, serum biomarkers and risk of atrial fibrillation: an exposure-wide umbrella review of meta-analyses.
European journal of epidemiology · 2020
Global PAD prevalence and risk factors (Fowkes 2013)2 links
Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis.
Lancet (London, England) · 2013
Anthropometric indicators and type 2 diabetes dose-response2 links
Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies.
BMJ (Clinical research ed.) · 2022
Sedentary behaviour and incident type 2 diabetes dose-response2 links
Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis.
European journal of epidemiology · 2018
Total sedentary behaviour and TV viewing dose-response2 links
Association of total sedentary behaviour and television viewing with risk of overweight/obesity, type 2 diabetes and hypertension: A dose-response meta-analysis.
Diabetes, obesity & metabolism · 2019
Sleep quantity and quality and incident type 2 diabetes2 links
Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis.
Diabetes care · 2009
Umbrella review: psychiatric disorders and type 2 diabetes2 links
Psychiatric disorders as risk factors for type 2 diabetes: An umbrella review of systematic reviews with and without meta-analyses.
Diabetes research and clinical practice · 2021
Dietary factors and gout/hyperuricaemia meta-analysis2 links
Dietary factors and risk of gout and hyperuricemia: a meta-analysis and systematic review.
Asia Pacific journal of clinical nutrition · 2018
Exposure-wide umbrella review of type 2 diabetes risk factors2 links
Risk factors for type 2 diabetes mellitus: An exposure-wide umbrella review of meta-analyses.
PloS one · 2018
Metabolic risk factors and advanced liver disease meta-analysis2 links
Metabolic risk factors and incident advanced liver disease in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of population-based observational studies.
PLoS medicine · 2020
Heavy metals and CKD meta-analysis2 links
Associations between exposure to heavy metals and the risk of chronic kidney disease: a systematic review and meta-analysis.
Critical reviews in toxicology · 2021
Diet and IBD risk meta-analysis of prospective cohorts2 links
Impact of diet on inflammatory bowel disease risk: systematic review, meta-analyses and implications for prevention.
EClinicalMedicine · 2025
Smoking and COPD systematic review with meta-analysis2 links
Systematic review with meta-analysis of the epidemiological evidence relating smoking to COPD, chronic bronchitis and emphysema.
BMC pulmonary medicine · 2011
Long-term air pollution and COPD incidence meta-analysis2 links
Impact of long-term exposure to ambient air pollution on the incidence of chronic obstructive pulmonary disease: A systematic review and meta-analysis.
Environmental research · 2021
Sleep duration and dementia meta-analysis2 links
Sleep Duration and the Risk of Dementia: A Systematic Review and Meta-analysis of Prospective Cohort Studies.
J Am Med Dir Assoc · 2019
Hernan: smoking, coffee and Parkinson's disease2 links
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease.
Ann Neurol · 2002
Head injury and dementia/AD meta-analysis (32 studies)2 links
Head Injury as a Risk Factor for Dementia and Alzheimer's Disease: A Systematic Review and Meta-Analysis of 32 Observational Studies.
PLoS One · 2017
Blood pressure and cognitive disorders meta-analysis (209 studies)2 links
Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies.
Hypertension · 2020
Long-term PM2.5 and IHD/stroke events2 links
Long-Term PMExposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta-Analysis.
Journal of the American Heart Association · 2020
InterConnect meat and incident type 2 diabetes2 links
Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries.
The lancet. Diabetes & endocrinology · 2024
Diabetes and dementia/AD meta-analysis2 links
Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies.
Journal of diabetes investigation · 2013
Household air pollution and adverse health effects meta-analysis2 links
Adverse health effects associated with household air pollution: a systematic review, meta-analysis, and burden estimation study.
The Lancet. Global health · 2020
Blood pressure and stroke subtypes Mendelian randomisation2 links
Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.
Neurology · 2020
Lifestyle factors and stroke subtypes: Mendelian randomisation2 links
Modifiable Lifestyle Factors and Risk of Stroke: A Mendelian Randomization Analysis.
Stroke · 2021
Smoking and atherosclerotic CVD: Mendelian randomisation (CAD, PAD, stroke)2 links
Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study.
JAMA network open · 2021
Smoking and pathological types of stroke: dose-response meta-analysis of cohorts2 links
Cigarette Smoking and Risk of Different Pathologic Types of Stroke: A Systematic Review and Dose-Response Meta-Analysis.
Frontiers in neurology · 2022
Coxib and traditional NSAID Trialists' (CNT) Collaboration2 links
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.
Lancet (London, England) · 2013
Systolic blood pressure and stroke or IHD, 124 cohorts (sex-specific)2 links
Comparison of the sex-specific associations between systolic blood pressure and the risk of cardiovascular disease: a systematic review and meta-analysis of 124 cohort studies, including 1.2 million individuals.
Stroke · 2013
Blood pressure and stroke: overview of published reviews2 links
Blood pressure and stroke: an overview of published reviews.
Stroke · 2004
Risk factors for intracerebral haemorrhage, systematic review2 links
Risk factors for intracerebral hemorrhage in the general population: a systematic review.
Stroke · 2003
Alcohol and stroke types, 27 prospective studies2 links
Differing association of alcohol consumption with different stroke types: a systematic review and meta-analysis.
BMC medicine · 2016
Waist-to-hip ratio, type 2 diabetes and CHD: Mendelian randomisation2 links
Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease.
JAMA · 2017
Alcohol consumption and eight cardiovascular diseases: Mendelian randomisation2 links
Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study.
Circulation. Genomic and precision medicine · 2020
Alcohol and atrial fibrillation: ALDH2 Mendelian randomisation (Korea)2 links
Causal Association Between Alcohol Consumption and Atrial Fibrillation: A Mendelian Randomization Study.
Korean circulation journal · 2022
Alcohol and atrial fibrillation: two-sample MR (null)2 links
No association between alcohol consumption and risk of atrial fibrillation: A two-sample Mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020
Alcohol ADH1B Mendelian randomisation1 link
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
BMJ (Clinical research ed.) · 2014
IPD-Work Consortium: job strain1 link
Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data
Lancet (London, England) · 2012
REDUCE-IT1 link
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
The New England journal of medicine · 2019
Salt reduction Cochrane meta-analysis1 link
Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials
BMJ (Clinical research ed.) · 2013
Childhood/adolescent excess weight and MS1 link
Excess Body Weight during Childhood and Adolescence Is Associated with the Risk of Multiple Sclerosis: A Meta-Analysis.
Neuroepidemiology · 2016
BMI and MS meta-analysis1 link
Abnormal body mass index is associated with risk of multiple sclerosis: A systematic review and meta-analysis.
Obesity research & clinical practice · 2024
Physical activity and incident hypertension1 link
Dose-Response Association Between Physical Activity and Incident Hypertension: A Systematic Review and Meta-Analysis of Cohort Studies.
Hypertension (Dallas, Tex. : 1979) · 2017
DASH adherence and hypertension risk1 link
Adherence to the DASH Diet and Risk of Hypertension: A Systematic Review and Meta-Analysis.
Nutrients · 2023
DASH adherence and diabetes risk1 link
Adherence to the dietary approaches to stop hypertension diet reduces the risk of diabetes mellitus: a systematic review and dose-response meta-analysis.
Endocrine · 2024
Early-life antibiotics and child obesity1 link
Dose-response association of early-life antibiotic exposure and subsequent overweight or obesity in children: A meta-analysis of prospective studies.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
Breastfeeding and early childhood obesity1 link
A Meta-Analysis of the Association Between Breastfeeding and Early Childhood Obesity.
Journal of pediatric nursing · 2020
E-values for ultra-processed food and weight gain1 link
Causality or confounding? Applying E values to examine associations between ultra-processed food consumption and risk of weight gain.
International journal of obesity (2005) · 2024
Cannabis dose and psychosis risk1 link
Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis.
Schizophrenia bulletin · 2016
Screen time and adolescent obesity1 link
Screen time increases overweight and obesity risk among adolescents: a systematic review and dose-response meta-analysis.
BMC primary care · 2022
Mendelian randomisation: BMI and psoriasis1 link
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.
PLoS medicine · 2019
Obesity and low back pain meta-analysis1 link
The association between obesity and low back pain: a meta-analysis.
American journal of epidemiology · 2009
SOS project: NSAIDs and upper GI complications1 link
Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project).
Drug safety · 2012
Cochrane: H. pylori eradication for peptic ulcer1 link
Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people.
The Cochrane database of systematic reviews · 2016
H. pylori and NSAIDs in peptic ulcer disease1 link
Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis.
Lancet (London, England) · 2002
Smokeless tobacco and periodontitis1 link
Smokeless tobacco and periodontitis: A systematic review with meta-analysis.
Journal of periodontal research · 2024
Fibre and diverticular disease1 link
Dietary fibre intake and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies.
European journal of nutrition · 2019
Umbrella review: dietary fibre1 link
The impact of dietary fiber consumption on human health: An umbrella review of evidence from 17,155,277 individuals.
Clinical nutrition (Edinburgh, Scotland) · 2025
Body composition and migraine1 link
Body composition status and the risk of migraine: A meta-analysis.
Neurology · 2017
BMI categories and primary headache1 link
Primary headache disorders and body mass index categories: A systematic review and dose-response meta-analysis.
Headache · 2022
Diabetes and open-angle glaucoma1 link
Diabetes mellitus as a risk factor for open-angle glaucoma: a systematic review and meta-analysis.
PloS one · 2014
Bisphenol A and type 2 diabetes1 link
Bisphenol A exposure and type 2 diabetes mellitus risk: a meta-analysis.
BMC endocrine disorders · 2018
Critical review of BPA epidemiology1 link
Bisphenol A and indicators of obesity, glucose metabolism/type 2 diabetes and cardiovascular disease: a systematic review of epidemiologic research.
Critical reviews in toxicology · 2014
Damp and mould and new asthma1 link
Residential dampness and molds and the risk of developing asthma: a systematic review and meta-analysis.
PloS one · 2012
Cleaning products and asthma in hospital staff1 link
The relationship between cleaning product exposure and respiratory and skin symptoms among healthcare workers in a hospital setting: A systematic review and meta-analysis.
Health science reports · 2022
Antidepressants and fracture risk1 link
Osteoporosis and Fracture Risk Associated with Novel Antidepressants: A Systematic Review and Meta-Analysis.
Actas espanolas de psiquiatria · 2024
Flu vaccine trials in heart disease1 link
Impact of Influenza Vaccination on Mortality and Major Cardiovascular Events in Adults with Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Vaccines · 2026
Lipoprotein(a) and calcific aortic valve disease1 link
Association Between Lipoprotein(a) and Calcific Aortic Valve Disease: A Systematic Review and Meta-Analysis.
Frontiers in cardiovascular medicine · 2022
LPA gene variants and aortic valve stenosis1 link
Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification.
JAMA cardiology · 2019
Whole and refined grains and diabetes1 link
Whole grain and refined grain consumption and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies.
European journal of epidemiology · 2013
White rice and cardiometabolic outcomes1 link
White rice consumption and risk of cardiometabolic and cancer outcomes: A systematic review and dose-response meta-analysis of prospective cohort studies.
Critical reviews in food science and nutrition · 2022
Plant-based diet index change and diabetes1 link
Changes in Plant-Based Diet Indices and Subsequent Risk of Type 2 Diabetes in Women and Men: Three U.S. Prospective Cohorts.
Diabetes care · 2021
Potassium intake and stroke1 link
Potassium-rich diet and risk of stroke: updated meta-analysis.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2014
Nuts and body weight1 link
Are fatty nuts a weighty concern? A systematic review and meta-analysis and dose-response meta-regression of prospective cohorts and randomized controlled trials.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
Mendelian randomisation: adiposity and sleep apnoea1 link
Causal effects of basal metabolic rate and adiposity on obstructive sleep apnea: univariable, multivariable, and bidirectional Mendelian randomization evidence.
Future science OA · 2026
GLP-1 drug trials in sleep apnoea1 link
Efficacy and safety of GLP-1 receptor agonists in the management of obstructive sleep apnea in individuals without diabetes: A systematic review and meta-analysis of randomized, placebo-controlled trials.
Sleep medicine · 2025
Sleep apnoea and alcohol, caffeine and tobacco1 link
Association between obstructive sleep apnea and alcohol, caffeine and tobacco: A meta-analysis.
Journal of oral rehabilitation · 2018
Alcohol and breathing during sleep1 link
The impact of alcohol on breathing parameters during sleep: A systematic review and meta-analysis.
Sleep medicine reviews · 2018
Smoking and diabetic retinopathy1 link
The association of smoking and risk of diabetic retinopathy in patients with type 1 and type 2 diabetes: a meta-analysis.
Endocrine · 2018
High blood pressure and erectile dysfunction1 link
Relation between hypertension and erectile dysfunction: a meta-analysisof cross-section studies.
International journal of impotence research · 2018
Cannabis use and erectile dysfunction1 link
Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.
American journal of men's health · 2019
Pooled cohorts: job insecurity and heart disease1 link
Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2013
Drinking pattern and ischaemic heart disease1 link
Alcohol consumption, drinking patterns, and ischemic heart disease: a narrative review of meta-analyses and a systematic review and meta-analysis of the impact of heavy drinking occasions on risk for moderate drinkers.
BMC medicine · 2014
Breakfast skipping and type 2 diabetes1 link
Breakfast Skipping Is Associated with Increased Risk of Type 2 Diabetes among Adults: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.
The Journal of nutrition · 2019
Trials of skipping breakfast and cardiovascular risk markers1 link
Effect of skipping breakfast on cardiovascular risk factors: a grade-assessed systematic review and meta-analysis of randomized controlled trials and prospective cohort studies.
Frontiers in endocrinology · 2023
Cold spells and health worldwide1 link
Global Association of Cold Spells and Adverse Health Effects: A Systematic Review and Meta-Analysis.
Environmental health perspectives · 2015
Multimorbidity and dementia risk1 link
Association between multimorbidity and the risk of dementia: A systematic review and meta-analysis.
Archives of gerontology and geriatrics · 2025
Dietary sugar and incident type 2 diabetes1 link
Dietary Sugar Intake and Incident Type 2 Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
Advances in nutrition (Bethesda, Md.) · 2025
Umbrella review: eggs and human health1 link
Egg consumption and human health: an umbrella review of observational studies.
International journal of food sciences and nutrition · 2019
Non-nutritive sweeteners and cardiometabolic health1 link
Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies.
CMAJ : Canadian Medical Association journal · 2017
Smoking in pregnancy and childhood obesity1 link
Meta-Analysis on Associations of Timing of Maternal Smoking Cessation Before and During Pregnancy With Childhood Overweight and Obesity.
Nicotine & tobacco research · 2023
Pregnancy exposures and eczema in the child1 link
Prenatal Maternal Risk Factors Contributing to Atopic Dermatitis: A Systematic Review and Meta-Analysis of Cohort Studies.
Annals of dermatology · 2023
Opioids and hip fracture1 link
Opioids increase hip fracture risk: a meta-analysis.
Journal of bone and mineral metabolism · 2016
Opioids, falls and fractures in older adults1 link
Opioid Use and the Risk of Falls, Fall Injuries and Fractures among Older Adults: A Systematic Review and Meta-Analysis.
The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Oral steroids and hip fracture, adjusted for disease severity1 link
Use of inhaled and oral glucocorticoids, severity of inflammatory disease and risk of hip/femur fracture: a population-based case-control study.
Journal of internal medicine · 2007
Pooled cohorts: corticosteroid use and fracture1 link
A meta-analysis of prior corticosteroid use and fracture risk.
Journal of bone and mineral research · 2004
Sleep irregularity and cardiovascular events1 link
Sleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.
Journal of the American College of Cardiology · 2020
Sleep regularity and mortality1 link
Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study.
Sleep · 2024
Built environment and diabetes1 link
Built environmental characteristics and diabetes: a systematic review and meta-analysis.
BMC medicine · 2018
Neighbourhood walkability, obesity and diabetes over time1 link
Association of Neighborhood Walkability With Change in Overweight, Obesity, and Diabetes.
JAMA · 2016
Preterm birth and chronic kidney disease1 link
Preterm birth and risk of chronic kidney disease from childhood into mid-adulthood: national cohort study.
BMJ (Clinical research ed.) · 2019
Preterm birth and diabetes1 link
Preterm birth and risk of type 1 and type 2 diabetes: a national cohort study.
Diabetologia · 2019
PFAS and high blood pressure1 link
The Association of Hypertension with Perfluoroalkyl and Polyfluoroalkyl Substances.
International heart journal · 2023
Long-term particulate matter and cardiometabolic disease1 link
Associations of long-term particulate matter exposure with cardiometabolic diseases: A systematic review and meta-analysis.
The Science of the total environment · 2023
Road traffic noise and hypertension1 link
Residential road traffic noise as a risk factor for hypertension in adults: Systematic review and meta-analysis of analytic studies published in the period 2011-2017.
Environmental pollution · 2018
Alcohol and incident high blood pressure1 link
Race- and sex-specific association between alcohol consumption and hypertension in 22 cohort studies: A systematic review and meta-analysis.
Nutrition, metabolism, and cardiovascular diseases · 2020
Trials of cutting down alcohol and blood pressure1 link
The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis.
The Lancet. Public health · 2017
Body-mass index and venous clots1 link
Relationship between body mass index, risk of venous thromboembolism and pulmonary embolism: A systematic review and dose-response meta-analysis of cohort studies among four million participants.
Thrombosis research · 2020
Coffee and gallstone disease1 link
Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease.
Alimentary pharmacology & therapeutics · 2015
Smoking and diverticular disease1 link
Tobacco smoking and the risk of diverticular disease - a systematic review and meta-analysis of prospective studies.
Colorectal disease · 2017
Lifestyle and diverticulitis in men1 link
Adherence to a Healthy Lifestyle is Associated With a Lower Risk of Diverticulitis among Men.
The American journal of gastroenterology · 2017
Parental separation and psychosis1 link
Psychosis in children of separated parents: A systematic review and meta-analysis.
European psychiatry · 2020
Childhood adversity in schizophrenia1 link
Childhood adversity in schizophrenia: a systematic meta-analysis.
Psychological medicine · 2012
Fitness and common mental health disorders1 link
The association between cardiorespiratory fitness and the incidence of common mental health disorders: A systematic review and meta-analysis.
Journal of affective disorders · 2019
Erectile dysfunction in diabetes1 link
High prevalence of erectile dysfunction in diabetes: a systematic review and meta-analysis of 145 studies.
Diabetic medicine · 2017
Long working hours and 50 health outcomes1 link
Long working hours and risk of 50 health conditions and mortality outcomes: a multicohort study in four European countries.
The Lancet regional health. Europe · 2021
E-cigarettes and asthma1 link
Association between e-cigarette use and asthma: a systematic review and meta-analysis.
The Journal of asthma · 2021
SSRIs added to NSAIDs and stomach bleeding1 link
Selective serotonin reuptake inhibitors increase risk of upper gastrointestinal bleeding when used with NSAIDs: a systemic review and meta-analysis.
Scientific reports · 2022
SSRIs, NSAIDs and upper gut bleeding1 link
Meta-analysis of the risk of upper gastrointestinal hemorrhage with combination therapy of selective serotonin reuptake inhibitors and non-steroidal anti-inflammatory drugs.
Biological & pharmaceutical bulletin · 2014
Umbrella review and Mendelian randomisation: adiposity and cardiovascular disease1 link
Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies.
European heart journal · 2021
Umbrella review: coffee and health1 link
Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes.
BMJ (Clinical research ed.) · 2017
Perceived racism and incident diabetes, Black Women's Health Study1 link
Perceived racism and incident diabetes in the Black Women's Health Study.
Diabetologia · 2017
Racism and obesity incidence, Black Women's Health Study1 link
Racism, segregation, and risk of obesity in the Black Women's Health Study.
American journal of epidemiology · 2014
Meta-analysis: perceived ethnic discrimination and psychotic symptoms1 link
Perceived ethnic discrimination as a risk factor for psychotic symptoms: a systematic review and meta-analysis.
Psychological medicine · 2020
Caregiving and coronary heart disease, Nurses' Health Study1 link
Caregiving and risk of coronary heart disease in U.S. women: a prospective study.
American journal of preventive medicine · 2003
Informal caregiving and coronary heart disease, Whitehall II1 link
Informal caregiving and the risk for coronary heart disease: the Whitehall II study.
The journals of gerontology. Series A, Biological sciences and medical sciences · 2013
Meta-analysis: breakfast skipping and overweight or obesity1 link
Skipping breakfast is associated with overweight and obesity: A systematic review and meta-analysis.
Obesity research & clinical practice · 2020
Trial meta-analysis: breakfast skipping and body composition1 link
Breakfast Skipping, Body Composition, and Cardiometabolic Risk: A Systematic Review and Meta-Analysis of Randomized Trials.
Obesity (Silver Spring, Md.) · 2020
Meta-analysis: job insecurity, unemployment and depressive symptoms1 link
Perceived job insecurity, unemployment and depressive symptoms: a systematic review and meta-analysis of prospective observational studies.
International archives of occupational and environmental health · 2016
Meta-analysis: foods with added fructose and fatty liver1 link
Meta-analysis of the association between major foods with added fructose and non-alcoholic fatty liver disease.
Food & function · 2023
Meta-analysis: body-mass index, waist circumference and erectile dysfunction1 link
Associations between body mass index, waist circumference and erectile dysfunction: a systematic review and META-analysis.
Reviews in endocrine & metabolic disorders · 2020
Pooled analysis: long working hours and onset of depressive symptoms1 link
Long working hours and depressive symptoms: systematic review and meta-analysis of published studies and unpublished individual participant data.
Scandinavian journal of work, environment & health · 2018
Dose-response meta-analysis: egg consumption and type 2 diabetes1 link
Egg consumption and risk of type 2 diabetes: a prospective study and dose-response meta-analysis.
Diabetologia · 2016
Meta-analysis: insomnia and risk of hypertension1 link
Insomnia and the risk of hypertension: A meta-analysis of prospective cohort studies.
Sleep medicine reviews · 2021
Meta-analysis: e-cigarettes and myocardial infarction1 link
E-cigarettes and myocardial infarction: A systematic review and meta-analysis.
International journal of cardiology · 2022
Meta-analysis: oral versus non-oral hormone therapy and venous thromboembolism1 link
Risk of venous thromboembolism events in postmenopausal women using oral versus non-oral hormone therapy: A systematic review and meta-analysis.
Thrombosis research · 2018
Cochrane network meta-analysis: combined oral contraceptives and venous thrombosis1 link
Combined oral contraceptives: venous thrombosis.
The Cochrane database of systematic reviews · 2014
Meta-analysis: smoking and primary open-angle glaucoma1 link
The effect of smoking on the risk of primary open-angle glaucoma: an updated meta-analysis of six observational studies.
Public health · 2016
Mendelian randomisation: vitamin D and multiple sclerosis1 link
Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study.
PLoS medicine · 2015
Dose-response meta-analysis: sleep apnoea and hypertension1 link
Relationship between obstructive sleep apnoea syndrome and essential hypertension: a dose-response meta-analysis.
Sleep medicine · 2018
Meta-analysis: antibiotic exposure and inflammatory bowel disease1 link
The role of antibiotic exposure as risk factor for IBD epidemic: an updated meta-analysis.
Journal of gastroenterology and hepatology · 2024
Meta-analysis: refined grain intake and cardiovascular disease1 link
Refined grain intake and cardiovascular disease: Meta-analyses of prospective cohort studies.
Trends in cardiovascular medicine · 2024
Multi-cohort study: long working hours and atrial fibrillation1 link
Long working hours as a risk factor for atrial fibrillation: a multi-cohort study.
European heart journal · 2017
Meta-analysis: depressive symptoms and new episodes of low back pain1 link
Symptoms of Depression and Risk of New Episodes of Low Back Pain: A Systematic Review and Meta-Analysis.
Arthritis care & research · 2015
Meta-analysis: childhood antibiotic exposure and long-term health outcomes1 link
Antibiotic exposure and adverse long-term health outcomes in children: A systematic review and meta-analysis.
The Journal of infection · 2022
Meta-analysis: shift work and obesity1 link
Meta-analysis on shift work and risks of specific obesity types.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018
Cardiorespiratory fitness meta-analysis1 link
Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis.
JAMA · 2009
SSB and coronary heart disease meta-analysis1 link
Sugar sweetened beverages consumption and risk of coronary heart disease: a meta-analysis of prospective studies.
Atherosclerosis · 2014
Fructose food sources and CVD dose-response meta-analysis1 link
The Relationship Between Major Food Sources of Fructose and Cardiovascular Outcomes: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.
Advances in nutrition (Bethesda, Md.) · 2022
Ultra-processed food dose-response meta-analysis1 link
Dose-response meta-analysis of ultra-processed food with the risk of cardiovascular events and all-cause mortality: evidence from prospective cohort studies.
Food & function · 2023
Depression and coronary heart disease meta-analysis1 link
Depression increased risk of coronary heart disease: A meta-analysis of prospective cohort studies.
Frontiers in cardiovascular medicine · 2022
Insomnia umbrella review1 link
Insomnia and multiple health outcomes: umbrella review of meta-analyses of prospective cohort studies.
Public health · 2023
Insomnia and cardiovascular disease meta-analysis1 link
Insomnia and risk of cardiovascular disease: a meta-analysis.
European journal of preventive cardiology · 2014
Shift work and vascular events meta-analysis1 link
Shift work and vascular events: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2012
Depression and stroke meta-analysis1 link
Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review.
JAMA · 2011
Gestational diabetes and cardiovascular disease meta-analysis1 link
Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis.
Diabetologia · 2019
HIV and atherosclerotic cardiovascular disease meta-analysis1 link
Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis.
Circulation · 2018
Periodontal disease and CHD incidence meta-analysis1 link
Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis.
Journal of general internal medicine · 2008
Grip strength and cardiovascular disease meta-analysis1 link
Association of Grip Strength With Risk of All-Cause Mortality, Cardiovascular Diseases, and Cancer in Community-Dwelling Populations: A Meta-analysis of Prospective Cohort Studies.
Journal of the American Medical Directors Association · 2017
Multiple adverse childhood experiences meta-analysis1 link
The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis.
The Lancet. Public health · 2017
Atrial fibrillation outcomes meta-analysis1 link
Atrial fibrillation and risks of cardiovascular disease, renal disease, and death: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2016
Cochrane review: combined oral contraceptives1 link
Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke.
The Cochrane database of systematic reviews · 2015
Oral contraceptives and thromboembolic events meta-analysis1 link
Risk of acute thromboembolic events with oral contraceptive use: a systematic review and meta-analysis.
Obstetrics and gynecology · 2013
Urate Mendelian randomisation and trials1 link
Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Hypertension (Dallas, Tex. : 1979) · 2020
WHO/ILO occupational noise and IHD1 link
The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury.
Environment international · 2021
Age at menopause and cardiovascular outcomes meta-analysis1 link
Association of Age at Onset of Menopause and Time Since Onset of Menopause With Cardiovascular Outcomes, Intermediate Vascular Traits, and All-Cause Mortality: A Systematic Review and Meta-analysis.
JAMA cardiology · 2016
NSAIDs and myocardial infarction IPD meta-analysis1 link
Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data.
BMJ (Clinical research ed.) · 2017
NSAID cardiovascular safety network meta-analysis1 link
Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis.
BMJ (Clinical research ed.) · 2011
Tooth loss and CVD dose-response meta-analysis1 link
Tooth loss and risk of cardiovascular disease and stroke: A dose-response meta analysis of prospective cohort studies.
PloS one · 2018
Environmental tobacco smoke and stroke meta-analysis1 link
Environmental Tobacco Smoke Exposure and Risk of Stroke in Never Smokers: An Updated Review with Meta-Analysis.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2016
PubMed 27765554 doi:10.1016/j.jstrokecerebrovasdis.2016.09.011
Loneliness/isolation and CHD and stroke meta-analysis1 link
Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies.
Heart (British Cardiac Society) · 2016
ERFC: lipoprotein(a)1 link
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.
JAMA · 2009
ESCAPE: air pollution and cerebrovascular events1 link
Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project.
Environmental health perspectives · 2014
Smokeless tobacco and MI/stroke meta-analysis1 link
Use of smokeless tobacco and risk of myocardial infarction and stroke: systematic review with meta-analysis.
BMJ (Clinical research ed.) · 2009
Saturated and trans fat and CVD meta-analysis1 link
Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies.
BMJ (Clinical research ed.) · 2015
ESCAPE: air pollution and acute coronary events1 link
Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project.
BMJ (Clinical research ed.) · 2014
WHO environmental noise guidelines review1 link
WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Cardiovascular and Metabolic Effects: A Summary.
International journal of environmental research and public health · 2018
Metabolic syndrome and cardiovascular risk meta-analysis1 link
The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis.
Journal of the American College of Cardiology · 2010
Vitamin D Mendelian randomisation and CAD1 link
Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease.
Circulation. Cardiovascular genetics · 2016
Sedentary time and CVD dose-response meta-analysis1 link
Continuous Dose-Response Association Between Sedentary Time and Risk for Cardiovascular Disease: A Meta-analysis.
JAMA cardiology · 2016
Non-occupational physical activity dose-response meta-analysis1 link
Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.
British journal of sports medicine · 2023
Diabetes and heart failure, sex-specific meta-analysis1 link
Diabetes as a risk factor for heart failure in women and men: a systematic review and meta-analysis of 47 cohorts including 12 million individuals.
Diabetologia · 2019
Diabetes and incident heart failure with/without CVD1 link
Diabetes and risk of heart failure in people with and without cardiovascular disease: systematic review and meta-analysis.
Diabetes research and clinical practice · 2023
Alcohol and heart failure (Suita + meta-analysis)1 link
Alcohol consumption and the risk of heart failure: the Suita Study and meta-analysis of prospective cohort studies.
Environmental health and preventive medicine · 2023
Alcohol and heart failure, 13 prospective studies1 link
Alcohol consumption and risk of heart failure: Meta-analysis of 13 prospective studies.
Clinical nutrition (Edinburgh, Scotland) · 2017
Physical activity and heart failure dose-response meta-analysis1 link
Physical activity and the risk of heart failure: a systematic review and dose-response meta-analysis of prospective studies.
European journal of epidemiology · 2020
Physical activity dose and heart failure risk1 link
Dose-Response Relationship Between Physical Activity and Risk of Heart Failure: A Meta-Analysis.
Circulation · 2015
Adiposity and atrial fibrillation dose-response meta-analysis1 link
Body mass index, abdominal fatness, fat mass and the risk of atrial fibrillation: a systematic review and dose-response meta-analysis of prospective studies.
European journal of epidemiology · 2017
Alcohol and atrial fibrillation dose-response meta-analysis1 link
Alcohol Consumption and Risk of Atrial Fibrillation: A Dose-Response Meta-Analysis of Prospective Studies.
Frontiers in cardiovascular medicine · 2022
Smoking and atrial fibrillation meta-analysis1 link
Tobacco smoking and the risk of atrial fibrillation: A systematic review and meta-analysis of prospective studies.
European journal of preventive cardiology · 2018
Sleep apnoea-hypopnoea and atrial fibrillation meta-analysis1 link
Association between Sleep Apnea Hypopnea Syndrome and the Risk of Atrial Fibrillation: A Meta-Analysis of Cohort Study.
BioMed research international · 2018
Cardiorespiratory fitness and incident atrial fibrillation1 link
Dose-response relationship of cardiorespiratory fitness with incident atrial fibrillation.
Heart failure reviews · 2020
Type 2 diabetes and atrial fibrillation meta-analysis1 link
Meta-analysis of cohort and case-control studies of type 2 diabetes mellitus and risk of atrial fibrillation.
The American journal of cardiology · 2011
Diabetes and incident peripheral arterial disease by sex1 link
Diabetes as a risk factor for incident peripheral arterial disease in women compared to men: a systematic review and meta-analysis.
Cardiovascular diabetology · 2020
Global PAD prevalence and risk factors 2015 update1 link
Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis.
The Lancet. Global health · 2019
Smoking and abdominal aortic aneurysm meta-analysis1 link
Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies.
Scientific reports · 2018
Blood pressure and abdominal aortic aneurysm meta-analysis1 link
Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies.
European journal of epidemiology · 2019
Adiposity and aortic aneurysm meta-analysis1 link
Adiposity and the risk of aortic aneurysm: results from the UK Biobank, Japan-Specific Health Check-ups Study and a systematic review and meta-analysis of cohort studies.
European journal of epidemiology · 2026
CKD Prognosis Consortium: kidney measures and incident PAD1 link
Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data.
The lancet. Diabetes & endocrinology · 2017
Usual blood pressure and peripheral arterial disease (4.2 million adults)1 link
Usual blood pressure, peripheral arterial disease, and vascular risk: cohort study of 4.2 million adults.
BMJ (Clinical research ed.) · 2015
Dietary fibre and type 2 diabetes dose-response1 link
Dietary fiber intake and risk of type 2 diabetes: a dose-response analysis of prospective studies.
European journal of epidemiology · 2014
Ultra-processed food and type 2 diabetes meta-analysis1 link
Ultra-processed food and risk of type 2 diabetes: a systematic review and meta-analysis of longitudinal studies.
International journal of epidemiology · 2022
Ultra-processed food and diabetes dose-response1 link
Ultra-Processed Food Consumption and Adult Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis.
Nutrients · 2021
Sleep duration and type 2 diabetes dose-response1 link
Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies.
Diabetes care · 2015
Shift work and diabetes meta-analysis1 link
Shift work and diabetes mellitus: a meta-analysis of observational studies.
Occupational and environmental medicine · 2014
Night shift work and type 2 diabetes cohort meta-analysis1 link
Association between night shift work and the risk of type 2 diabetes mellitus: a cohort-based meta-analysis.
BMC endocrine disorders · 2024
Obstructive sleep apnoea and type 2 diabetes dose-response1 link
Obstructive sleep apnea and risk of type 2 diabetes mellitus: A systematic review and dose-response meta-analysis of cohort studies.
Journal of diabetes · 2020
Progression to type 2 diabetes after gestational diabetes1 link
Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis.
BMJ (Clinical research ed.) · 2020
Type 2 diabetes after gestational diabetes (Lancet 2009)1 link
Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis.
Lancet (London, England) · 2009
PCOS and long-term cardiometabolic disease1 link
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis.
Human reproduction update · 2020
PCOS and type 2 diabetes, role of obesity1 link
Risk of type 2 diabetes mellitus in polycystic ovary syndrome is associated with obesity: a meta-analysis of observational studies.
Endocrine · 2021
Depression and type 2 diabetes bidirectional meta-analysis1 link
Depression and type 2 diabetes over the lifespan: a meta-analysis.
Diabetes care · 2008
Socioeconomic position and type 2 diabetes incidence1 link
Type 2 diabetes incidence and socio-economic position: a systematic review and meta-analysis.
International journal of epidemiology · 2011
Dairy products and type 2 diabetes dose-response1 link
Dairy products consumption and risk of type 2 diabetes: systematic review and dose-response meta-analysis.
PloS one · 2013
Dairy products and obesity, hypertension and type 2 diabetes1 link
Consumption of Dairy Products and the Risk of Overweight or Obesity, Hypertension, and Type 2 Diabetes Mellitus: A Dose-Response Meta-Analysis and Systematic Review of Cohort Studies.
Advances in nutrition (Bethesda, Md.) · 2022
Coffee and type 2 diabetes dose-response meta-analysis1 link
Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis.
Diabetes care · 2014
Birth weight and type 2 diabetes (JAMA 2008)1 link
Birth weight and risk of type 2 diabetes: a systematic review.
JAMA · 2008
Birth weight and type 2 diabetes dose-response1 link
Birth weight and risk of type 2 diabetes: A dose-response meta-analysis of cohort studies.
Diabetes/metabolism research and reviews · 2019
Childhood obesity as predictor of adult morbidity1 link
Childhood obesity as a predictor of morbidity in adulthood: a systematic review and meta-analysis.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015
Obesity and incident NAFLD, 21 cohorts1 link
Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21 cohort studies.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016
Sugar-sweetened beverages and NAFLD dose-response1 link
Consumption of Sugar-Sweetened Beverages Has a Dose-Dependent Effect on the Risk of Non-Alcoholic Fatty Liver Disease: An Updated Systematic Review and Dose-Response Meta-Analysis.
International journal of environmental research and public health · 2019
Sugar-sweetened beverages and NAFLD meta-analysis1 link
Association of sugar sweetened beverages consumption with non-alcoholic fatty liver disease: a systematic review and meta-analysis.
European journal of nutrition · 2018
Ultra-processed food and NAFLD meta-analysis1 link
Ultra-Processed Food Intake Is Associated with Non-Alcoholic Fatty Liver Disease in Adults: A Systematic Review and Meta-Analysis.
Nutrients · 2023
Ultra-processed food and NAFLD dose-response (2025)1 link
Ultra-processed foods and non-alcoholic fatty liver disease: an updated systematic review and dose-response meta-analysis.
Frontiers in nutrition · 2025
Physical activity and NAFLD risk meta-analysis1 link
Association between physical activity and risk of nonalcoholic fatty liver disease: a meta-analysis.
Therapeutic advances in gastroenterology · 2017
Coffee and NAFLD incidence, prevalence and fibrosis1 link
Effect of Coffee Consumption on Non-Alcoholic Fatty Liver Disease Incidence, Prevalence and Risk of Significant Liver Fibrosis: Systematic Review with Meta-Analysis of Observational Studies.
Nutrients · 2021
BMI and gout dose-response meta-analysis1 link
Body mass index and the risk of gout: a systematic review and dose-response meta-analysis of prospective studies.
European journal of nutrition · 2014
Obesity, hypertension and diuretics as gout risk factors1 link
Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.
Arthritis research & therapy · 2018
Alcohol and hyperuricaemia/gout meta-analysis1 link
Impact of alcohol consumption on hyperuricemia and gout: a systematic review and meta-analysis.
Frontiers in nutrition · 2025
Sugar-sweetened beverages, fructose and gout1 link
Consumption of sugar sweetened beverages and dietary fructose in relation to risk of gout and hyperuricemia: a systematic review and meta-analysis.
Critical reviews in food science and nutrition · 2018
Fructose-containing sugar sources and incident gout1 link
Important food sources of fructose-containing sugars and incident gout: a systematic review and meta-analysis of prospective cohort studies.
BMJ open · 2019
CKD and incident gout (Framingham)1 link
Chronic kidney disease as a risk factor for incident gout among men and women: retrospective cohort study using data from the Framingham Heart Study.
BMJ open · 2015
Arsenic exposure and type 2 diabetes dose-response1 link
An updated systematic review and dose-response meta-analysis on the relation between exposure to arsenic and risk of type 2 diabetes.
Toxicology letters · 2023
Low-level drinking-water arsenic and type 2 diabetes1 link
Low-level exposure to arsenic in drinking water and risk of type 2 diabetes: a systematic review and meta-analysis.
European journal of epidemiology · 2026
Umbrella review of serum uric acid and health outcomes1 link
Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies.
BMJ (Clinical research ed.) · 2017
Alcohol and gout Mendelian randomisation1 link
The Relationship between Alcohol Consumption and Gout: A Mendelian Randomization Study.
Genes · 2022
Alcoholic beverages and incident gout (UK Biobank)1 link
Consumption of Total and Specific Alcoholic Beverages and Long-Term Risk of Gout Among Men and Women.
JAMA network open · 2024
Periodontitis and type 2 diabetes epidemiological relationship1 link
Epidemiologic relationship between periodontitis and type 2 diabetes mellitus.
BMC oral health · 2020
Breastfeeding and maternal type 2 diabetes dose-response1 link
Breastfeeding and the maternal risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2013
PCOS and NAFLD meta-analysis1 link
A potential link between polycystic ovary syndrome and non-alcoholic fatty liver disease: an update meta-analysis.
Reproductive health · 2018
PCOS and NAFLD updated meta-analysis1 link
Association between polycystic ovary syndrome and risk of non-alcoholic fatty liver disease: a meta-analysis.
Endokrynologia Polska · 2023
Hepato-ovarian axis Mendelian randomisation1 link
The hepato-ovarian axis: genetic evidence for a causal association between non-alcoholic fatty liver disease and polycystic ovary syndrome.
BMC medicine · 2023
Adverse childhood experiences and type 2 diabetes1 link
Adverse childhood experiences and risk of type 2 diabetes: A systematic review and meta-analysis.
Metabolism: clinical and experimental · 2015
Metabolic syndrome and incident diabetes1 link
Metabolic syndrome and incident diabetes: current state of the evidence.
Diabetes care · 2008
Pesticides and diabetes meta-analysis1 link
Exposure to pesticides and diabetes: A systematic review and meta-analysis.
Environment international · 2016
Pesticide exposure and type 2 diabetes (2024)1 link
Impact of pesticides exposure and type 2 diabetes risk: a systematic review and meta-analysis.
Endocrine · 2024
Physical activity and type 2 diabetes dose-response1 link
Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis.
European journal of epidemiology · 2015
Blood pressure and heart failure meta-analysis1 link
Blood pressure, hypertension, and the risk of heart failure: a systematic review and meta-analysis of cohort studies.
European journal of preventive cardiology · 2024
BMI, abdominal fatness and heart failure dose-response1 link
Body Mass Index, Abdominal Fatness, and Heart Failure Incidence and Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.
Circulation · 2016
Smoking and heart failure meta-analysis1 link
Tobacco smoking and the risk of heart failure: A systematic review and meta-analysis of prospective studies.
European journal of preventive cardiology · 2018
Sleep Heart Health Study: OSA and incident heart failure1 link
Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study.
Circulation · 2010
Sleep-disordered breathing and incident heart failure (MrOS)1 link
Sleep-disordered Breathing and Incident Heart Failure in Older Men.
American journal of respiratory and critical care medicine · 2016
Air pollution and heart failure meta-analysis1 link
Global association of air pollution and heart failure: a systematic review and meta-analysis.
Lancet (London, England) · 2013
Blood pressure and atrial fibrillation meta-analysis1 link
Blood pressure, hypertension and the risk of atrial fibrillation: a systematic review and meta-analysis of cohort studies.
European journal of epidemiology · 2023
Blood pressure and twelve cardiovascular diseases (CALIBER)1 link
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Lancet (London, England) · 2014
Coffee and cirrhosis meta-analysis1 link
Systematic review with meta-analysis: coffee consumption and the risk of cirrhosis.
Alimentary pharmacology & therapeutics · 2016
Smoking and incident CKD meta-analysis1 link
Cigarette smoking and chronic kidney disease in the general population: a systematic review and meta-analysis of prospective cohort studies.
Nephrology, dialysis, transplantation · 2017
NSAIDs and CKD meta-analysis1 link
Non-steroidal anti-inflammatory drugs: what is the actual risk of chronic kidney disease? A systematic review and meta-analysis.
Romanian journal of internal medicine · 2025
Million Women Study: BMI and cirrhosis1 link
Body mass index and risk of liver cirrhosis in middle aged UK women: prospective study.
BMJ (Clinical research ed.) · 2010
UK Biobank: diabetes and cirrhosis1 link
Diabetes and the risk of cirrhosis and HCC: An analysis of the UK Biobank.
Hepatology communications · 2023
PPI use and incident CKD meta-analysis1 link
Association between Proton Pump Inhibitor Use and Risk of Incident Chronic Kidney Disease: Systematic Review and Meta-Analysis.
Biomedicines · 2024
Job-exposure-matrix occupational COPD meta-analysis1 link
Occupational COPD and job exposure matrices: a systematic review and meta-analysis.
International journal of chronic obstructive pulmonary disease · 2017
Serum urate and incident CKD meta-analysis1 link
Serum uric acid is associated with incident chronic kidney disease in middle-aged populations: a meta-analysis of 15 cohort studies.
PloS one · 2014
Ambient air pollution and CKD meta-analysis1 link
Ambient air pollution exposure and risk of chronic kidney disease: A systematic review of the literature and meta-analysis.
Environmental research · 2021
Environmental cadmium and CKD meta-analysis1 link
Association of cadmium environmental exposure with chronic kidney disease: A systematic review and meta-analysis.
The Science of the total environment · 2023
Pre-eclampsia and later CKD meta-analysis1 link
Pre-eclampsia is associated with later kidney chronic disease and end-stage renal disease: Systematic review and meta-analysis of observational studies.
Pregnancy hypertension · 2020
Low birth weight and CKD systematic review1 link
Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies.
American journal of kidney diseases · 2009
Environmental risk factors for CKDnt meta-analysis1 link
Environmental risk factors for chronic kidney disease of non-traditional causes in tropical coastal areas: A systematic review and meta-analysis.
PLoS neglected tropical diseases · 2025
Global COPD prevalence and risk factors 20191 link
Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis.
The Lancet. Respiratory medicine · 2022
Early-life exposures and adult COPD meta-analysis1 link
Impact of early life exposures on COPD in adulthood: A systematic review and meta-analysis.
Respirology (Carlton, Vic.) · 2021
COPD in the global HIV population meta-analysis1 link
Prevalence of chronic obstructive pulmonary disease in the global population with HIV: a systematic review and meta-analysis.
The Lancet. Global health · 2017
Prediabetes and incident CKD meta-analysis1 link
Association between prediabetes and risk of chronic kidney disease: a systematic review and meta-analysis.
Diabetic medicine · 2016
Respirable silica and chronic renal disease meta-analysis1 link
Occupational exposure to respirable crystalline silica and chronic non-malignant renal disease: systematic review and meta-analysis.
International archives of occupational and environmental health · 2017
Overweight, obesity and incident asthma meta-analysis1 link
Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies.
American journal of respiratory and critical care medicine · 2007
CARTA Mendelian randomisation: smoking and asthma1 link
Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium.
Scientific reports · 2017
Smoking and fracture risk meta-analysis (FRAX cohorts)1 link
Smoking and fracture risk: a meta-analysis.
Osteoporosis international · 2004
Smoking and fracture: FRAX update meta-analysis1 link
A meta-analysis of smoking and fracture risk to update the FRAX® tool.
Osteoporosis international · 2026
Alcohol intake as a risk factor for fracture1 link
Alcohol intake as a risk factor for fracture.
Osteoporosis international · 2004
Alcohol intake and fracture cohort meta-analysis1 link
A systematic review and meta-analysis of prospective cohort studies on the association between alcohol intake and risk of fracture.
Critical reviews in food science and nutrition · 2021
Physical activity and osteoporotic fracture meta-analysis1 link
The association between physical activity and osteoporotic fractures: a review of the evidence and implications for future research.
Annals of epidemiology · 2008
Age at menopause and fracture meta-analysis1 link
Association between age at menopause and fracture risk: a systematic review and meta-analysis.
Endocrine · 2018
PPI use and fracture meta-analysis1 link
Proton-pump Inhibitor Use and Fracture Risk: An Updated Systematic Review and Meta-analysis.
Journal of bone metabolism · 2018
Benzodiazepines and fracture meta-analysis1 link
Association between use of benzodiazepines and risk of fractures: a meta-analysis.
Osteoporosis international · 2013
Cadmium exposure and fracture meta-analysis1 link
Cadmium Exposure and Risk of Any Fracture: A PRISMA-Compliant Systematic Review and Meta-Analysis.
Medicine · 2016
BMI as a predictor of fracture risk (pooled cohorts)1 link
Body mass index as a predictor of fracture risk: a meta-analysis.
Osteoporosis international · 2005
Obesity and knee osteoarthritis meta-analysis1 link
What if we prevent obesity? Risk reduction in knee osteoarthritis estimated through a meta-analysis of observational studies.
Arthritis care & research · 2011
Occupational risk in knee osteoarthritis meta-analysis1 link
Occupational Risk in Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Observational Studies.
Arthritis care & research · 2020
Knee extensor weakness and incident knee OA meta-analysis1 link
Knee extensor muscle weakness is a risk factor for the development of knee osteoarthritis: an updated systematic review and meta-analysis including 46 819 men and women.
British journal of sports medicine · 2021
Smoking and risk of rheumatoid arthritis meta-analysis1 link
Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies.
Annals of the rheumatic diseases · 2010
Smoking pack-years and RA dose-response meta-analysis1 link
Cigarette smoking and risk of rheumatoid arthritis: a dose-response meta-analysis.
Arthritis research & therapy · 2014
Periodontitis and RA risk meta-analysis1 link
Rheumatoid arthritis risk in periodontitis patients: A systematic review and meta-analysis.
Joint bone spine · 2020
BMI and RA risk dose-response meta-analysis1 link
Body mass index and the risk of rheumatoid arthritis: a systematic review and dose-response meta-analysis.
Arthritis research & therapy · 2015
Crystalline silica and RA meta-analysis1 link
Systematic Review and Meta-analysis on the Association of Occupational Exposure to Free Crystalline Silica and Rheumatoid Arthritis.
Clinical reviews in allergy & immunology · 2021
Smoking and IBD risk meta-analysis (by ethnicity)1 link
Ethnic Differences in the Smoking-related Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
Journal of Crohn's & colitis · 2021
Ultra-processed food and IBD dose-response meta-analysis1 link
The association of ultra-processed food consumption with adult inflammatory bowel disease risk: a systematic review and dose-response meta-analysis of 4 035 694 participants.
Nutrition reviews · 2024
Dietary fibre, fruit, vegetables and IBD meta-analysis1 link
Association of Dietary Fiber, Fruit, and Vegetable Consumption with Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
Advances in nutrition · 2021
Smoking and AMD meta-analysis1 link
Smoking and the risk of age-related macular degeneration: a meta-analysis.
Annals of epidemiology · 2008
AMD risk factors updated meta-analysis1 link
Risk factors for age-related macular degeneration: Updated systematic review and meta-analysis.
Medicine · 2025
Dietary omega-3 and fish intake and AMD meta-analysis1 link
Dietary omega-3 polyunsaturated fatty acids and fish intake and risk of age-related macular degeneration.
Clinical nutrition (Edinburgh, Scotland) · 2021
Cochrane: omega-3 supplements for AMD1 link
Omega 3 fatty acids for preventing or slowing the progression of age-related macular degeneration.
The Cochrane database of systematic reviews · 2015
Smoking and age-related cataract meta-analysis1 link
Smoking and risk of age-related cataract: a meta-analysis.
Investigative ophthalmology & visual science · 2012
Type 2 diabetes and cataract meta-analysis1 link
Meta-analysis of the risk of cataract in type 2 diabetes.
BMC ophthalmology · 2014
Obesity and age-related cataract dose-response meta-analysis1 link
Association between obesity and age-related cataract: an updated systematic review and dose-response meta-analysis of prospective cohort studies.
Frontiers in nutrition · 2024
Smoking and hearing loss meta-analysis1 link
Effect of smoking on hearing loss: quality assessment and meta-analysis.
Preventive medicine · 2005
Diabetes and hearing impairment meta-analysis1 link
Diabetes and risk of hearing impairment in adults: a meta-analysis.
The Journal of clinical endocrinology and metabolism · 2012
Alcohol consumption and liver cirrhosis meta-analysis1 link
Alcohol Consumption and Risk of Liver Cirrhosis: A Systematic Review and Meta-Analysis.
The American journal of gastroenterology · 2019
Obesity and onset of CKD meta-analysis1 link
A systematic review and meta-analysis suggests obesity predicts onset of chronic kidney disease in the general population.
Kidney international · 2017
Serum 25(OH)D and fracture meta-analysis1 link
The associations between serum 25-hydroxyvitamin D level and the risk of total fracture and hip fracture.
Osteoporosis international · 2017
Hypertension and incident CKD/ESRD meta-analysis (sex-specific)1 link
The impact of hypertension on chronic kidney disease and end-stage renal disease is greater in men than women: a systematic review and meta-analysis.
BMC nephrology · 2020
Secondhand smoke and COPD meta-analysis1 link
Secondhand Smoke Exposure and the Risk of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.
International journal of chronic obstructive pulmonary disease · 2023
WHI: oestrogen plus progestin and fracture1 link
Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial.
JAMA · 2003
Sleep apnoea and cognitive impairment meta-analysis1 link
Association between sleep apnoea and risk of cognitive impairment and Alzheimer's disease: a meta-analysis of cohort-based studies.
Sleep Breath · 2023
Cochrane: anticholinergic burden and dementia1 link
Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome.
Cochrane Database Syst Rev · 2021
Coupland anticholinergic drugs and dementia1 link
Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study.
JAMA Intern Med · 2019
Umbrella review: benzodiazepines and dementia1 link
Benzodiazepine Use and the Risk of Dementia in the Elderly Population: An Umbrella Review of Meta-Analyses.
J Pers Med · 2023
PPIs and dementia meta-analysis with bias analysis1 link
Do proton pump inhibitors increase the risk of dementia? A systematic review, meta-analysis and bias analysis.
Br J Clin Pharmacol · 2022
Periodontal disease and cognitive disorders meta-analysis1 link
The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis.
Age Ageing · 2023
Tooth loss and cognitive function meta-analysis1 link
Tooth Loss Increases the Risk of Diminished Cognitive Function: A Systematic Review and Meta-analysis.
JDR Clin Trans Res · 2016
MIND diet and dementia cohort meta-analysis1 link
Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia.
JAMA Psychiatry · 2023
Occupational toxins and Parkinson's disease meta-analysis1 link
Exposure to toxic occupations and their association with Parkinson's disease: a systematic review with meta-analysis.
Rev Environ Health · 2021
TBI and Parkinson's disease meta-analysis1 link
Traumatic brain injury and risk of Parkinson's disease: a meta-analysis.
Acta Neurol Belg · 2023
TBI and Alzheimer's disease cohort meta-analysis1 link
A meta-analysis of cohort studies: Traumatic brain injury and risk of Alzheimer's Disease.
PLoS One · 2021
TBI in veterans and incident dementia meta-analysis1 link
Traumatic brain injuries among veterans and the risk of incident dementia: A systematic review & meta-analysis.
Age Ageing · 2022
IPD-Work: job strain and clinical depression1 link
Job strain as a risk factor for clinical depression: systematic review and meta-analysis with additional individual participant data.
Psychol Med · 2017
Insomnia as a predictor of depression meta-analysis1 link
Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies.
J Affect Disord · 2011
Physical activity and incident depression meta-analysis1 link
Physical Activity and Incident Depression: A Meta-Analysis of Prospective Cohort Studies.
Am J Psychiatry · 2018
Dose-response: physical activity and depression1 link
Association Between Physical Activity and Risk of Depression: A Systematic Review and Meta-analysis.
JAMA Psychiatry · 2022
Ultra-processed food and health meta-analysis1 link
Consumption of ultra-processed foods and health status: a systematic review and meta-analysis.
Br J Nutr · 2020
Socioeconomic status and dementia meta-analysis1 link
Socioeconomic Status and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 39 Prospective Studies.
J Prev Alzheimers Dis · 2023
Social class and dementia meta-analysis1 link
Social class and the risk of dementia: A systematic review and meta-analysis of the prospective longitudinal studies.
Scand J Public Health · 2022
Antihypertensive medications and dementia IPD meta-analysis1 link
Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.
Lancet Neurol · 2019
Handgrip strength and cognitive outcomes meta-analysis1 link
Handgrip strength and risk of cognitive outcomes: new prospective study and meta-analysis of 16 observational cohort studies.
Geroscience · 2022
Grip strength and cognitive decline/dementia meta-analysis1 link
Grip Strength and the Risk of Cognitive Decline and Dementia: A Systematic Review and Meta-Analysis of Longitudinal Cohort Studies.
Front Aging Neurosci · 2021
Loneliness and onset of mental health problems meta-analysis1 link
Loneliness and the onset of new mental health problems in the general population.
Soc Psychiatry Psychiatr Epidemiol · 2022
Umbrella review: factors associated with loneliness1 link
Factors Associated With Loneliness: An Umbrella Review Of Observational Studies.
J Affect Disord · 2020
VITAL-DEP randomised trial1 link
Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial.
JAMA · 2020
Serum 25(OH)D and depression meta-analysis1 link
Serum 25-hydroxyvitamin D levels and the risk of depression: a systematic review and meta-analysis.
J Nutr Health Aging · 2013
Fish and PUFA intake and cognitive impairment dose-response1 link
Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies.
Am J Clin Nutr · 2016
Childhood maltreatment and adult depression (prospective)1 link
Maltreatment in childhood substantially increases the risk of adult depression and anxiety in prospective cohort studies: systematic review, meta-analysis, and proportional attributable fractions.
Psychol Med · 2015
Agreement between prospective and retrospective maltreatment measures1 link
Agreement Between Prospective and Retrospective Measures of Childhood Maltreatment: A Systematic Review and Meta-analysis.
JAMA Psychiatry · 2019
Mediterranean diet and depression meta-analysis1 link
Adherence to the Mediterranean diet and risk of depression: a systematic review and updated meta-analysis of observational studies.
Nutr Rev · 2019
Meta-analysis of modifiable risk factors for Alzheimer's disease1 link
Meta-analysis of modifiable risk factors for Alzheimer's disease.
J Neurol Neurosurg Psychiatry · 2015
Cash transfers and common mental disorders meta-analysis of RCTs1 link
Do cash transfers alleviate common mental disorders in low- and middle-income countries? A systematic review and meta-analysis.
PLoS One · 2023
Fish consumption and CHD meta-analysis1 link
Fish Consumption and Coronary Heart Disease: A Meta-Analysis.
Nutrients · 2020
Solid fuel use and cardiovascular events1 link
Solid fuel use and cardiovascular events: A systematic review and meta-analysis of observational studies.
Indoor air · 2021
Low eGFR and incident stroke1 link
Low glomerular filtration rate and risk of stroke: meta-analysis.
BMJ (Clinical research ed.) · 2010
Air pollution and heart failure meta-analysis1 link
Effect of Air Pollution on Heart Failure: Systematic Review and Meta-Analysis.
Environmental health perspectives · 2023
LDL-C and micro/macrovascular disease (MR)1 link
Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study.
Journal of the American College of Cardiology · 2019
Overweight/obesity and diabetes risk1 link
The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies.
Diabetes research and clinical practice · 2010
Smoking and incident type 2 diabetes1 link
Relation of active, passive, and quitting smoking with incident type 2 diabetes: a systematic review and meta-analysis.
The lancet. Diabetes & endocrinology · 2015
Statins and incident diabetes (CTT-style trial meta)1 link
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials.
Lancet (London, England) · 2010
25(OH)D and incident type 2 diabetes1 link
Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of prospective studies.
Diabetologia · 2012
25(OH)D metabolites and T2D (MR)1 link
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
PLoS medicine · 2020
PM10/PM2.5 and type 2 diabetes1 link
Ambient air fine particulate matter (PM10 and PM2.5) and risk of type 2 diabetes mellitus and mechanisms of effects: a global systematic review and meta-analysis.
International journal of environmental health research · 2024
Low education and dementia risk1 link
What does (low) education mean in terms of dementia risk? A systematic review and meta-analysis highlighting inconsistency in measuring and operationalising education.
SSM - population health · 2020
Camp Lejeune TCE and Parkinson disease1 link
Risk of Parkinson Disease Among Service Members at Marine Corps Base Camp Lejeune.
JAMA neurology · 2023
Smoking and major psychiatric disorders1 link
Association between cigarette smoking and the risk of major psychiatric disorders: a systematic review and meta-analysis in depression, schizophrenia, and bipolar disorder.
Frontiers in medicine · 2025
Lifetime smoking and depression (MR)1 link
Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.
Psychological medicine · 2019
Neighbourhood socioeconomic conditions and depression1 link
Neighborhood socioeconomic conditions and depression: a systematic review and meta-analysis.
Social psychiatry and psychiatric epidemiology · 2015
Long-term air pollution and type 2 diabetes1 link
Associations between long-term exposure to ambient air pollution and risk of type 2 diabetes mellitus: A systematic review and meta-analysis.
Environmental pollution (Barking, Essex : 1987) · 2019
Ambient air pollution and diabetes meta-analysis1 link
Ambient air pollution and diabetes: A systematic review and meta-analysis.
Environmental research · 2019
Nut consumption and type 2 diabetes (updated)1 link
Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies.
The American journal of clinical nutrition · 2021
Food groups and type 2 diabetes (12 food groups)1 link
Food groups and risk of type 2 diabetes mellitus: a systematic review and meta-analysis of prospective studies.
European journal of epidemiology · 2017
Mediterranean diet adherence and diabetes risk1 link
Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis.
Public health nutrition · 2015
Dietary patterns and type 2 diabetes1 link
Dietary Patterns and Type 2 Diabetes: A Systematic Literature Review and Meta-Analysis of Prospective Studies.
The Journal of nutrition · 2017
Alcohol use disorders, intake and later depression1 link
Effect of alcohol use disorders and alcohol intake on the risk of subsequent depressive symptoms: a systematic review and meta-analysis of cohort studies.
Addiction (Abingdon, England) · 2020
Green space and depression/anxiety meta-analysis1 link
Green space exposure on depression and anxiety outcomes: A meta-analysis.
Environmental research · 2023
Occupational particles and incident COPD (Stockholm cohort)1 link
Occupational exposure to particles and increased risk of developing chronic obstructive pulmonary disease (COPD): A population-based cohort study in Stockholm, Sweden.
Environmental research · 2021
WHO concentration-response functions for air pollution morbidity1 link
Choices of morbidity outcomes and concentration-response functions for health risk assessment of long-term exposure to air pollution.
Environmental epidemiology (Philadelphia, Pa.) · 2024
WHO AQG update: NO2 and ozone and mortality1 link
Long-Term Exposure to Nitrogen Dioxide and Ozone and Mortality: Update of the WHO Air Quality Guidelines Systematic Review and Meta-Analysis.
International journal of public health · 2024
Statin therapy and dose in peripheral arterial disease1 link
Effects of Statin Therapy and Dose on Cardiovascular and Limb Outcomes in Peripheral Arterial Disease: A Systematic Review and Meta-analysis.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2021
Statins and major adverse limb events in PAD1 link
Statins and Major Adverse Limb Events in Patients with Peripheral Artery Disease: A Systematic Review and Meta-Analysis.
Thrombosis and haemostasis · 2020
Socioeconomic inequalities in depression meta-analysis1 link
Socioeconomic inequalities in depression: a meta-analysis.
American journal of epidemiology · 2003
Cardiorespiratory fitness, strength and type 2 diabetes1 link
Cardiorespiratory fitness, muscular strength and risk of type 2 diabetes: a systematic review and meta-analysis.
Diabetologia · 2019
Mendelian randomisation: serum urate and gout1 link
Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.
Journal of the American College of Cardiology · 2016
Diabetes and periodontitis: meta-regression of longitudinal studies1 link
Does diabetes increase the risk of periodontitis? A systematic review and meta-regression analysis of longitudinal prospective studies.
Acta diabetologica · 2018
SPRINT MIND: intensive blood pressure control and dementia1 link
Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.
JAMA · 2019
Cochrane: blood pressure control for diabetic retinopathy (2023 update)1 link
Blood pressure control for diabetic retinopathy.
The Cochrane database of systematic reviews · 2023
Perceived stress and incident CHD meta-analysis1 link
Meta-analysis of perceived stress and its association with incident coronary heart disease.
The American journal of cardiology · 2012
Chronic heavy drinking and ischaemic heart disease meta-analysis1 link
Chronic heavy drinking and ischaemic heart disease: a systematic review and meta-analysis.
Open heart · 2014
DASH diet and coronary artery disease meta-analysis1 link
Dietary approach to stop hypertension diet and risk of coronary artery disease: a meta-analysis of prospective cohort studies.
International journal of food sciences and nutrition · 2019
Cumulative childhood adversity and adult cardiometabolic disease meta-analysis1 link
Cumulative childhood adversity and adult cardiometabolic disease: A meta-analysis.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
Childhood maltreatment genetics and Mendelian randomisation1 link
Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach.
The lancet. Psychiatry · 2021
Burden of Proof: systolic blood pressure and ischaemic heart disease1 link
Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study.
Nature medicine · 2022
Blood pressure and peripheral artery disease Mendelian randomisation1 link
Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease.
Arteriosclerosis, thrombosis, and vascular biology · 2021
Intensive blood pressure lowering and PAD: meta-analysis of trials1 link
Intensive blood pressure reduction but an increased risk of peripheral arterial disease: a systematic review and meta-analysis of randomized controlled trials.
Annals of medicine · 2025
EPA+DHA and CHD: meta-analysis of RCTs and cohorts1 link
A Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies of Eicosapentaenoic and Docosahexaenoic Long-Chain Omega-3 Fatty Acids and Coronary Heart Disease Risk.
Mayo Clinic proceedings · 2017
WHI hormone trials: intervention and post-stopping phases (2013)1 link
Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials.
JAMA · 2013
HRT and arterial and venous events: meta-analysis of RCTs1 link
Association between hormone replacement therapy and subsequent arterial and venous vascular events: a meta-analysis.
European heart journal · 2008
HRT and stroke: meta-analysis of RCTs1 link
Association between hormone replacement therapy and subsequent stroke: a meta-analysis.
BMJ (Clinical research ed.) · 2005
Cochrane: hormone therapy for preventing cardiovascular disease1 link
Hormone therapy for preventing cardiovascular disease in post-menopausal women.
The Cochrane database of systematic reviews · 2015
WHI: oestrogen plus progestin and stroke1 link
Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial.
JAMA · 2003
NO2 and mortality: systematic review of cohorts (Stieb 2021)1 link
Systematic review and meta-analysis of cohort studies of long term outdoor nitrogen dioxide exposure and mortality.
PloS one · 2021
Type 2 diabetes and CHD: Mendelian randomisation1 link
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.
Nature communications · 2015
Diabetes, blood glucose and heart failure: meta-analysis of prospective studies1 link
Diabetes mellitus, blood glucose and the risk of heart failure: A systematic review and meta-analysis of prospective studies.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2018
Type 2 diabetes and heart failure: Mendelian randomisation (HERMES)1 link
Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study.
Diabetes care · 2021
Socioeconomic status, vascular risk factors and stroke incidence meta-analysis1 link
Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis.
Cerebrovascular diseases (Basel, Switzerland) · 2011
Education, cognition, CHD and ischaemic stroke: Mendelian randomisation1 link
Education protects against coronary heart disease and stroke independently of cognitive function: evidence from Mendelian randomization.
International journal of epidemiology · 2019
Lipid-lowering therapy and major adverse limb events: meta-analysis of RCTs1 link
Effects of lipid-lowering therapy on major adverse limb events in patients with peripheral arterial disease: A meta-analysis of randomized clinical trials.
Vascular · 2022
Circulating 25(OH)D and cardiovascular disease: meta-analysis of prospective studies1 link
Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies.
Circulation. Cardiovascular quality and outcomes · 2012
Alcohol and dementia: IPD-Work consortium (7 cohorts)1 link
Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption With Risk for Dementia.
JAMA network open · 2020
Midlife hypertension and Alzheimer's disease meta-analysis1 link
Midlife Hypertension and Alzheimer's Disease: A Systematic Review and Meta-Analysis.
Journal of Alzheimer's disease : JAD · 2019
Social relationships and dementia meta-analysis1 link
Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies.
Ageing research reviews · 2015
Physical activity and dementia meta-analysis (58 studies)1 link
Physical activity as a protective factor for dementia and Alzheimer's disease: systematic review, meta-analysis and quality assessment of cohort and case-control studies.
British journal of sports medicine · 2022
Smoking and dementia meta-analysis (37 studies)1 link
Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers.
PloS one · 2015
TBI and dementia meta-analysis (32 studies, civilians and veterans)1 link
Systematic Review, Meta-Analysis, and Population Attributable Risk of Dementia Associated with Traumatic Brain Injury in Civilians and Veterans.
Journal of neurotrauma · 2023
Education and dementia meta-analysis (2006)1 link
Education and dementia: a meta-analytic study.
Neuroepidemiology · 2006
Benzodiazepines and dementia meta-analysis (nested case-control and cohort studies)1 link
Association between Benzodiazepine Use and Dementia: A Meta-Analysis.
PloS one · 2015
Benzodiazepines and dementia meta-analysis with lag-time analysis1 link
A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias.
CNS drugs · 2018
Mediterranean, DASH and MIND diets and dementia: meta-analysis of cohort studies1 link
Dietary Patterns and Risk of Dementia in Elderly Individuals: A Systematic Review and Meta-analysis of Cohort Studies.
Nutrition reviews · 2026
Green spaces and common psychiatric disorders meta-analysis1 link
Green spaces exposure and the risk of common psychiatric disorders: A meta-analysis.
SSM - population health · 2024
Education and late-life depression meta-analysis1 link
Education and risk for late life depression: a meta-analysis of published literature.
International journal of psychiatry in medicine · 2010
Mendelian randomisation: smoking and multiple sclerosis (Mitchell)1 link
Little evidence for an effect of smoking on multiple sclerosis risk: A Mendelian Randomization study.
PLoS biology · 2020
Mendelian randomisation: smoking and multiple sclerosis (Vandebergh)1 link
Smoking and multiple sclerosis risk: a Mendelian randomization study.
Journal of neurology · 2020
Extreme temperature and COPD morbidity and mortality meta-analysis1 link
Extreme temperature increases the risk of COPD morbimortality: A systematic review and meta-analysis.
The Science of the total environment · 2025
Corrigendum: extreme temperature and COPD meta-analysis (corrected estimates)1 link
Corrigendum to 'Extreme temperature increases the risk of COPD morbimortality: A systematic review and meta-analysis [Science of The Total Environment, Vol 958 [2025] 178087'.
The Science of the total environment · 2025
Preterm birth and type 1 and type 2 diabetes meta-analysis1 link
Preterm birth and risk of type 1 and type 2 diabetes: systematic review and meta-analysis.
Obesity reviews : an official journal of the International Association for the Study of Obesity · 2014
Hormone therapy and fracture: meta-analysis of randomised trials1 link
Effect of hormone therapy on the risk of bone fractures: a systematic review and meta-analysis of randomized controlled trials.
Menopause (New York, N.Y.) · 2016
Cochrane: long-term hormone therapy after the menopause (2026 version)1 link
Long-term hormone therapy for perimenopausal and postmenopausal women.
The Cochrane database of systematic reviews · 2026
High triglycerides and type 2 diabetes dose-response meta-analysis1 link
Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis.
Frontiers in endocrinology · 2025
Mendelian randomisation: triglycerides and type 2 diabetes1 link
Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.
Diabetes · 2011
Diabetes and chronic kidney disease in women and men meta-analysis1 link
Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men: a systematic review and meta-analysis.
Endocrine · 2017
Alcohol and liver cirrhosis dose-response, 44 studies1 link
How does alcohol use impact morbidity and mortality of liver cirrhosis? A systematic review and dose-response meta-analysis.
Hepatology international · 2024
Alcohol intake and liver cirrhosis meta-analysis (Corrao)1 link
Meta-analysis of alcohol intake in relation to risk of liver cirrhosis.
Alcohol and alcoholism (Oxford, Oxfordshire) · 1998
Diabetes and incident CHD, 64 cohorts (sex-specific)1 link
Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 individuals and 28,203 coronary events.
Diabetologia · 2014
Diabetes and fatal CHD, 37 cohorts (sex-specific)1 link
Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies.
BMJ (Clinical research ed.) · 2006
Emerging Risk Factors Collaboration: diabetes and cause-specific death1 link
Diabetes mellitus, fasting glucose, and risk of cause-specific death.
The New England journal of medicine · 2011
Umbrella review: risk factors for NAFLD1 link
Associations of Nutritional, Lifestyle, and Metabolic Factors With Non-alcoholic Fatty Liver Disease: An Umbrella Review With More Than 380,000 Participants.
Frontiers in nutrition · 2021
Global NAFLD incidence, 63 cohort studies1 link
Global incidence of non-alcoholic fatty liver disease: A systematic review and meta-analysis of 63 studies and 1,201,807 persons.
Journal of hepatology · 2023
Smoking and PAD in women and men, 4 cohorts1 link
Smoking as a risk factor for lower extremity peripheral artery disease in women compared to men: A systematic review and meta-analysis.
PloS one · 2024
Cigarette smoking and PAD meta-analysis (55 studies)1 link
Meta-analysis of the association between cigarette smoking and peripheral arterial disease.
Heart (British Cardiac Society) · 2014
Risk factors for subarachnoid haemorrhage, updated review1 link
Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies.
Stroke · 2005
Risk factors for abdominal aortic aneurysm, 34 studies1 link
Risk factors for abdominal aortic aneurysm in general populations: A systematic review and meta-analysis.
PloS one · 2025
GBD 2021 household air pollution1 link
Global, regional, and national burden of household air pollution, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
Lancet (London, England) · 2025
Obesity and low back pain, 10 cohorts1 link
Obesity as a Risk Factor for Low Back Pain: A Meta-Analysis.
Clinical spine surgery · 2018
Alcohol intake and stroke dose-response, 27 prospective studies1 link
Alcohol intake and risk of stroke: a dose-response meta-analysis of prospective studies.
International journal of cardiology · 2014
WHO guidelines for indoor air quality: dampness and mould (2009)1 link
WHO Guidelines for Indoor Air Quality: Dampness and Mould
WHO Regional Office for Europe · 2009
ESCAPE: air pollution and adult asthma, 6 cohorts1 link
Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE).
Environmental health perspectives · 2015
Adverse pregnancy outcomes and maternal CKD, 23 studies1 link
Adverse Pregnancy Outcomes and Long-term Maternal Kidney Disease: A Systematic Review and Meta-analysis.
JAMA network open · 2020
Pre-eclampsia and later CKD or ESKD, 21 papers1 link
A systematic review and meta-analysis indicates long-term risk of chronic and end-stage kidney disease after preeclampsia.
Kidney international · 2019
WHO/ILO: long working hours and IHD, 37 studies1 link
The effect of exposure to long working hours on ischaemic heart disease: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury.
Environment international · 2020
Smoking and colonic diverticulosis, 3 cohorts1 link
Smoking and risk of colonic diverticulosis: A meta-analysis.
Journal of postgraduate medicine · 2018
Smoking and alcohol and diverticulosis, 62 studies1 link
Smoking and alcohol consumption as risk factors for colonic diverticulosis and its complications: Systematic review and meta-analysis.
Medicine · 2026
Smokeless tobacco and periodontitis in Asia, 36 studies1 link
Association between Smokeless Tobacco Use and Risk of Periodontitis in Asian Countries: A Systematic Review and Meta-Analysis.
Asian Pacific journal of cancer prevention : APJCP · 2021
Depression and stroke, 17 prospective studies1 link
Depression and risk of stroke: a meta-analysis of prospective studies.
Stroke · 2012
Depression and stroke risk, 44 studies1 link
Association between depression and stroke risk in adults: a systematic review and meta-analysis.
Frontiers in neurology · 2024
Major depression and ischaemic stroke subtypes, MR1 link
Major depression and small vessel stroke: a Mendelian randomization analysis.
Journal of neurology · 2019
Childhood BMI and multiple sclerosis, MR1 link
Childhood obesity and multiple sclerosis: A Mendelian randomization study.
Multiple sclerosis (Houndmills, Basingstoke, England) · 2021
Food insecurity and adult weight abnormality, 31 studies1 link
Food insecurity and adult weight abnormality risk: a systematic review and meta-analysis.
European journal of nutrition · 2019
Smoking and psoriasis dose-response, 30 studies1 link
Smoking, alcohol consumption, and psoriasis risk: a systematic review and dose-response meta-analysis of observational studies.
Frontiers in public health · 2026
Smoking status and psoriasis, 16 studies1 link
Smoking Status and Psoriasis Risk: An Updated Systematic Review and Meta-Analysis.
Dermatology (Basel, Switzerland) · 2026
Smoking and psoriasis risk meta-analysis1 link
Impact of smoking on psoriasis risk and treatment efficacy: a meta-analysis.
The Journal of international medical research · 2020
Type 2 diabetes and incident hearing loss, Nurses Health Studies1 link
Type 2 diabetes and the risk of incident hearing loss.
Diabetologia · 2019
COPD incidence in people with HIV, Ontario1 link
Incidence of chronic obstructive pulmonary disease in people with HIV in Ontario, 1996-2015: a retrospective population-based cohort study.
CMAJ open · 2020
Tooth loss and dementia, 18 cohort studies1 link
Tooth loss and the risk of cognitive decline and dementia: A meta-analysis of cohort studies.
Frontiers in neurology · 2023
Tooth loss and dementia dose-response, 14 studies1 link
Dose-Response Meta-Analysis on Tooth Loss With the Risk of Cognitive Impairment and Dementia.
Journal of the American Medical Directors Association · 2021
Education and major depression, network MR1 link
Four modifiable factors that mediate the effect of educational time on major depressive disorder risk: A network Mendelian randomization study.
PloS one · 2023
Education and mental disorders, MR1 link
Association of educational attainment with mental disorders and the mediation role of lifestyle factors: a Mendelian randomization study.
European archives of psychiatry and clinical neuroscience · 2026
Education and depressive symptoms, Young Finns MR1 link
Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization.
Preventive medicine · 2018
CPAP and glucose and lipids, 31 randomised trials1 link
Effect of Continuous Positive Airway Pressure on Glucose and Lipid Profiles in Patients With Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Archivos de bronconeumologia · 2023
PROBIT breastfeeding promotion trial, age 6.5 years1 link
A randomized breast-feeding promotion intervention did not reduce child obesity in Belarus.
The Journal of nutrition · 2009
PROBIT breastfeeding promotion trial, age 11.5 years1 link
Effects of promoting longer-term and exclusive breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial.
JAMA · 2013
Obesity and venous thromboembolism, MR1 link
Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.
Human genetics · 2017
Type 2 diabetes and ischaemic stroke subtypes, MR1 link
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study.
Neurology · 2017
Coffee intake and type 2 diabetes, MR (Copenhagen)1 link
Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: a Mendelian randomization study.
International journal of epidemiology · 2015
Coffee and type 2 diabetes, IHD, depression, Alzheimer disease, MR1 link
Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer's disease: a Mendelian randomization study.
Scientific reports · 2016
Coffee and type 2 diabetes in Koreans, MR1 link
Association of coffee consumption with type 2 diabetes and glycemic traits: a Mendelian randomization study.
Nutrition research and practice · 2023
Plasma caffeine and type 2 diabetes, MR1 link
Appraisal of the causal effect of plasma caffeine on adiposity, type 2 diabetes, and cardiovascular disease: two sample mendelian randomisation study.
BMJ medicine · 2023
Cochrane: exercise for preventing falls (108 trials)1 link
Exercise for preventing falls in older people living in the community.
The Cochrane database of systematic reviews · 2019
Cochrane: periodontal treatment and HbA1c (35 trials)1 link
Treatment of periodontitis for glycaemic control in people with diabetes mellitus.
The Cochrane database of systematic reviews · 2022
CBT for insomnia and incident major depression, older adults1 link
Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial.
JAMA psychiatry · 2022
Digital CBT for insomnia and depression prevention1 link
Depression prevention via digital cognitive behavioral therapy for insomnia: a randomized controlled trial.
Sleep · 2019
SHUTi online insomnia programme and depression (GoodNight)1 link
Effectiveness of an online insomnia program (SHUTi) for prevention of depressive episodes (the GoodNight Study): a randomised controlled trial.
The lancet. Psychiatry · 2016
ADVANCE intensive glucose control1 link
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.
The New England journal of medicine · 2008
ADVANCE kidney outcomes1 link
Intensive glucose control improves kidney outcomes in patients with type 2 diabetes.
Kidney international · 2013
E-cigarette use and respiratory disease in adults, PATH waves 1-31 link
Association of E-Cigarette Use With Respiratory Disease Among Adults: A Longitudinal Analysis.
American journal of preventive medicine · 2020
E-cigarette use and incident respiratory conditions, PATH waves 1-41 link
Association of Electronic Cigarette Use With Incident Respiratory Conditions Among US Adults From 2013 to 2018.
JAMA network open · 2020
HMGCR variants, statin trials and type 2 diabetes (genetic analysis)1 link
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Lancet (London, England) · 2015
Heart Protection Study: simvastatin and peripheral vascular events1 link
Randomized trial of the effects of cholesterol-lowering with simvastatin on peripheral vascular and other major vascular outcomes in 20,536 people with peripheral arterial disease and other high-risk conditions.
Journal of vascular surgery · 2007
LPA variants and coronary disease (PROCARDIS)1 link
Genetic variants associated with Lp(a) lipoprotein level and coronary disease.
The New England journal of medicine · 2009
Genetically elevated lipoprotein(a) and myocardial infarction (Copenhagen)1 link
Genetically elevated lipoprotein(a) and increased risk of myocardial infarction.
JAMA · 2009
Obesity and cerebrovascular disease: Mendelian randomisation (MEGASTROKE)1 link
Mendelian Randomization Study of Obesity and Cerebrovascular Disease.
Annals of neurology · 2020
Smoking, alcohol, coffee and fracture: Mendelian randomisation (UK Biobank)1 link
Associations of Smoking and Alcohol and Coffee Intake with Fracture and Bone Mineral Density: A Mendelian Randomization Study.
Calcified tissue international · 2019
Causal factors for knee, hip and hand osteoarthritis: MR in UK Biobank1 link
Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK Biobank.
Arthritis & rheumatology (Hoboken, N.J.) · 2019
Adiposity and gout: Mendelian randomisation1 link
Genetic association between adiposity and gout: a Mendelian randomization study.
Rheumatology (Oxford, England) · 2018
DASH trial: dietary patterns and blood pressure1 link
A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.
The New England journal of medicine · 1997
DASH diet and blood pressure: meta-analysis of 17 randomised trials1 link
Influence of Dietary Approaches to Stop Hypertension (DASH) diet on blood pressure: a systematic review and meta-analysis on randomized controlled trials.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2014
Obesity, diabetes, lifestyle and gallstone disease: Mendelian randomisation1 link
Obesity, Type 2 Diabetes, Lifestyle Factors, and Risk of Gallstone Disease: A Mendelian Randomization Investigation.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
Atrial fibrillation and stroke: Mendelian randomisation1 link
Causal relationship between atrial fibrillation and stroke risk: a Mendelian randomization.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
PubMed 38442074 doi:10.1016/j.jstrokecerebrovasdis.2023.107446
Phenome-wide bidirectional Mendelian randomisation of atrial fibrillation1 link
A phenome-wide bidirectional Mendelian randomization analysis of atrial fibrillation.
International journal of epidemiology · 2022
Antithrombotic therapy in atrial fibrillation: meta-analysis of 29 trials1 link
Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.
Annals of internal medicine · 2007
PubMed 17577005 doi:10.7326/0003-4819-146-12-200706190-00007
Physical activity, sedentary behaviour and type 2 diabetes: MR (2023)1 link
Physical Activity, Sedentary Behavior, and Type 2 Diabetes: Mendelian Randomization Analysis.
Journal of the Endocrine Society · 2023
Accelerometer-measured activity and type 2 diabetes: MR (2020)1 link
Association of physical activity and sedentary behavior with type 2 diabetes and glycemic traits: a two-sample Mendelian randomization study.
BMJ open diabetes research & care · 2020
Blood pressure and atrial fibrillation: Mendelian randomisation (2021)1 link
The relationship between blood pressure and risk of atrial fibrillation: a Mendelian randomization study.
European journal of preventive cardiology · 2021
Elevated blood pressure and atrial fibrillation: Mendelian randomisation (Genome Med)1 link
Genetic susceptibility, elevated blood pressure, and risk of atrial fibrillation: a Mendelian randomization study.
Genome medicine · 2021
Alcohol abstinence trial in drinkers with atrial fibrillation1 link
Alcohol Abstinence in Drinkers with Atrial Fibrillation.
The New England journal of medicine · 2020
Obesity and sleep apnoea in four community cohorts: IPD meta-analysis1 link
The relationship between obesity and obstructive sleep apnea in four community-based cohorts: an individual participant data meta-analysis of 12,860 adults.
EClinicalMedicine · 2025
Childhood BMI and adult type 2 diabetes, CHD and CKD: Mendelian randomisation1 link
Childhood BMI and Adult Type 2 Diabetes, Coronary Artery Diseases, Chronic Kidney Disease, and Cardiometabolic Traits: A Mendelian Randomization Analysis.
Diabetes care · 2018
Education and coronary heart disease: Mendelian randomisation1 link
Education and coronary heart disease: mendelian randomisation study.
BMJ (Clinical research ed.) · 2017
Lifelong lower LDL cholesterol and CHD: Mendelian randomisation1 link
Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis.
Journal of the American College of Cardiology · 2012
Genetic predisposition to higher blood pressure and coronary artery disease1 link
Genetic predisposition to higher blood pressure increases coronary artery disease risk.
Hypertension (Dallas, Tex. : 1979) · 2013
Triglyceride variants and coronary artery disease (genetic analysis)1 link
Common variants associated with plasma triglycerides and risk for coronary artery disease.
Nature genetics · 2013
Genetic liability to insomnia and nine cardiovascular diseases: MR1 link
Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study.
European journal of epidemiology · 2021
BMI and vascular-related dementia: Mendelian randomisation1 link
High Body Mass Index as a Causal Risk Factor for Vascular-Related Dementia: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism · 2026
Blood lipids and Alzheimer's disease: Mendelian randomisation1 link
Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.
PLoS medicine · 2014
Alcohol and incident dementia in current drinkers: linear and non-linear MR1 link
Association between alcohol consumption and incidence of dementia in current drinkers: linear and non-linear mendelian randomization analysis.
EClinicalMedicine · 2024
Obesity and multiple sclerosis: Mendelian randomisation1 link
Obesity and Multiple Sclerosis: A Mendelian Randomization Study.
PLoS medicine · 2016
Cannabis use and schizophrenia: Mendelian randomisation1 link
Cannabis use and risk of schizophrenia: a Mendelian randomization study.
Molecular psychiatry · 2018
Ultra-processed diet inpatient crossover trial (weight gain)1 link
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.
Cell metabolism · 2019
Physical activity and depression: bidirectional Mendelian randomisation1 link
Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study.
JAMA psychiatry · 2019
Exercise as a treatment for depression: meta-analysis of 25 trials1 link
Exercise as a treatment for depression: A meta-analysis adjusting for publication bias.
Journal of psychiatric research · 2016
ACHIEVE trial: hearing intervention and cognitive decline1 link
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial.
Lancet (London, England) · 2023
CKD-FIX: allopurinol and progression of chronic kidney disease1 link
Effects of Allopurinol on the Progression of Chronic Kidney Disease.
The New England journal of medicine · 2020
PERL: allopurinol and kidney function in type 1 diabetes1 link
Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes.
The New England journal of medicine · 2020
Genetic and clinical determinants of fracture: GWAS and Mendelian randomisation1 link
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.
BMJ (Clinical research ed.) · 2018
Blood lipids and ischaemic stroke subtypes: Mendelian randomisation1 link
Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes: A Mendelian Randomization Study.
Stroke · 2018
Alcohol and more than 200 diseases in Chinese men (China Kadoorie Biobank, genotype-predicted intake)1 link
Alcohol consumption and risks of more than 200 diseases in Chinese men.
Nature medicine · 2023
Exercise training and blood pressure: meta-analysis of 93 trials1 link
Exercise training for blood pressure: a systematic review and meta-analysis.
Journal of the American Heart Association · 2013
MIND diet trial for prevention of cognitive decline1 link
Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons.
The New England journal of medicine · 2023
Obesity and liver diseases: two-sample Mendelian randomisation1 link
Obesity and risk for liver disease: a two-sample Mendelian randomisation study.
The British journal of nutrition · 2024
Age at menopause and coronary heart disease: bidirectional Mendelian randomisation1 link
Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization.
The Journal of clinical endocrinology and metabolism · 2022
Menopausal timing and cardiovascular disease: meta-analysis of 17 MR studies1 link
Insights into the relationship between menopausal timing and risk of cardiovascular disease: a systematic review and meta-analysis of Mendelian randomization analyses.
Systematic reviews · 2026
Resistance exercise and lean body mass in older adults: meta-analysis of trials1 link
Influence of resistance exercise on lean body mass in aging adults: a meta-analysis.
Medicine and science in sports and exercise · 2011
Exercise interventions for fatty liver disease: meta-analysis of 28 trials1 link
Exercise-based Interventions for Nonalcoholic Fatty Liver Disease: A Meta-analysis and Meta-regression.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2016
PREDIMED trial: Mediterranean diet and incident depression1 link
Mediterranean dietary pattern and depression: the PREDIMED randomized trial.
BMC medicine · 2013
Cochrane: omega-3 fatty acids for preventing cognitive decline and dementia1 link
Omega 3 fatty acid for the prevention of cognitive decline and dementia.
The Cochrane database of systematic reviews · 2012
Cafe-PD trial: caffeine as symptomatic treatment for Parkinson's disease1 link
Caffeine as symptomatic treatment for Parkinson disease (Café-PD): A randomized trial.
Neurology · 2017
Febuxostat in early gout: randomised placebo-controlled trial1 link
Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.
Arthritis & rheumatology (Hoboken, N.J.) · 2017
PROGRESS trial: blood pressure lowering by stroke subtype1 link
Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial.
Stroke · 2004
BMI and cataract: Mendelian randomisation mediation analysis1 link
The role of metabolic factors in the causal association between body mass index and cataract: A Mendelian randomization mediation analysis.
Experimental eye research · 2026
BMI and asthma: Mendelian randomisation1 link
Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization.
Allergy · 2018
Smoking and rheumatoid arthritis: Mendelian randomisation1 link
Genetic predisposition to smoking is associated with risk of rheumatoid arthritis: a Mendelian randomization study.
Arthritis research & therapy · 2020
BMI and rheumatoid arthritis: Mendelian randomisation1 link
Causal association between body mass index and risk of rheumatoid arthritis: A Mendelian randomization study.
European journal of clinical investigation · 2019
Serum 25-hydroxyvitamin D and major depression: Mendelian randomisation1 link
Serum 25-Hydroxyvitamin D Concentrations and Major Depression: A Mendelian Randomization Study.
Nutrients · 2018
Vitamin D and depression: Mendelian randomisation (2019)1 link
Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study.
Nutrients · 2019
Smoking, alcohol and coffee and Parkinson's disease: MR (Courage-PD)1 link
Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease.
Journal of Parkinson's disease · 2022
Smoking and drinking and Parkinson's disease risk: Mendelian randomisation1 link
Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study.
Scientific reports · 2021
Blood pressure lowering and incident dementia: meta-analysis of 14 trials1 link
Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis.
JAMA · 2020
Weight loss and steatohepatitis: randomised trial1 link
Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis.
Hepatology (Baltimore, Md.) · 2010
IDEA trial: diet and exercise in knee osteoarthritis1 link
Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial.
JAMA · 2013
ENRICHD trial: treating depression after myocardial infarction1 link
Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.
JAMA · 2003
Commentary on the WHO/ILO review of long working hours and ischaemic heart disease (re-analysis by risk of bias and job status)1 link
The WHO/ILO report on long working hours and ischaemic heart disease - Conclusions are not supported by the evidence.
Environment international · 2020
Major depression and alcohol dependence: Mendelian randomisation (Psychiatric Genomics Consortium)1 link
Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium.
Psychological medicine · 2019
Parkinson's disease and ease of quitting smoking: Danish case-control study1 link
Parkinson disease and smoking revisited: ease of quitting is an early sign of the disease.
Neurology · 2014
WHI oestrogen plus progestin trial: venous thrombosis1 link
Estrogen plus progestin and risk of venous thrombosis.
JAMA · 2004